TG - Thyroglobulin - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Protein
Gene
References

 
TG »  Thyroglobulin  (Tg)
 
Gene name:  TG
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 148 2
GENE REF ISO

Function

 show evidences
Overview 
Precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3).  
1
  • UniProtKB
GO molecular function 
Carboxylic ester hydrolase activitydefinition[GO:0052689]  
1
  • RefGenome
Hormone activitydefinition[GO:0005179]  
1
  • UniProtKB KW
GO biological process 
Hormone biosynthetic processdefinition[GO:0042446]  
1
  • UniProtKB KW
Iodide transportdefinition[GO:0015705] silver  
1
  • Ortholog Compara
Regulation of myelinationdefinition[GO:0031641] silver  
1
  • Ortholog Compara
Signal transductiondefinition[GO:0007165]  
1
  • PINC
Thyroid gland developmentdefinition[GO:0030878]  
1
  • UniProtKB
Thyroid hormone metabolic processdefinition[GO:0042403] silver  
1
  • Ortholog Compara
Enzymatic activity 
 
More information is available from:
Pathways 
According to KEGG, this protein belongs to the following pathway:
Autoimmune thyroid disease  hsa05320+7038  
 
More information is available from:
 

Keywords

Biological process 
Thyroid hormones biosynthesis  definition   [KW-0893]
Molecular function 
Hormone  definition   [KW-0372]
Thyroid hormone  definition   [KW-0795]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: Thyroglobulin
GenomeRNAi: 7038
PRO: PR:P01266