ORM1 - Alpha-1-acid glycoprotein 1 - human protein (Function)
 
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ORM1 »  Alpha-1-acid glycoprotein 1  (AGP 1)
 
Protein also known as:  Orosomucoid-1 (OMD 1).
Gene name:  ORM1
Family name: Calycin » Lipocalin
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction.  
2
  • CuratedUniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
GO biological process 
Acute-phase responsedefinition[GO:0006953]  
  • IEAUniProtKB KW
Inflammatory responsedefinition[GO:0006954]  
1
  • TASPINC
Regulation of immune system processdefinition[GO:0002682] silver  
  • IEAInterPro 2 GO
Transportdefinition[GO:0006810]  
  • IEAUniProtKB KW
 

Keywords

Biological process 
Acute phase  definition   [KW-0011]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ORM1
GenomeRNAi: 5004
PRO: PR:P02763