AHSG - Alpha-2-HS-glycoprotein - human protein (Function)
 
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AHSG »  Alpha-2-HS-glycoprotein
 
Protein also known as:  Ba-alpha-2-glycoprotein. Cleaved into:  Alpha-2-HS-glycoprotein chain A; Alpha-2-HS-glycoprotein chain B.
Gene name:  AHSG
Family name: Fetuin
Entry whose protein(s) existence is based on evidence at protein level
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1 184 1
GENE REF ISO

Function

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Overview 
Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.  
  • CuratedUniProtKB
GO molecular function 
Cysteine-type endopeptidase inhibitor activitydefinition[GO:0004869] silver  
  • IEAInterPro 2 GO
Kinase inhibitor activitydefinition[GO:0019210]  
1
  • NASUniProtKB
GO biological process 
Acute-phase responsedefinition[GO:0006953]  
1
  • IDAUniProtKB
Negative regulation of bone mineralizationdefinition[GO:0030502]  
  • ISSOrtholog Curator
Negative regulation of endopeptidase activitydefinition[GO:0010951]  
  • IEAInterPro 2 GO
Negative regulation of insulin receptor signaling pathwaydefinition[GO:0046627]  
1
  • NASUniProtKB
Negative regulation of phosphorylationdefinition[GO:0042326]  
1
  • NASGOC
Ossificationdefinition[GO:0001503] silver  
  • IEAOrtholog Compara
Pinocytosisdefinition[GO:0006907]  
1
  • NASUniProtKB
Positive regulation of phagocytosisdefinition[GO:0050766]  
1
  • IDAUniProtKB
Regulation of bone mineralizationdefinition[GO:0030500]  
1
  • NASUniProtKB
Regulation of inflammatory responsedefinition[GO:0050727]  
1
  • IMPUniProtKB
Skeletal system developmentdefinition[GO:0001501]  
1
  • NASUniProtKB
Enzymatic activity 
 
More information is available from:
 

Keywords

Biological process 
Mineral balance  definition   [KW-0495]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: Alpha-2-HS-glycoprotein
GenomeRNAi: 197
PRO: PR:P02765