TTR - Transthyretin - human protein (Function)
 
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TTR »  Transthyretin
 
Gene name:  TTR
Family name: Transthyretin
Entry whose protein(s) existence is based on evidence at protein level
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1 412 1
GENE REF ISO

Function

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Overview 
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.  
1
  • CuratedUniProtKB
GO molecular function 
Hormone activitydefinition[GO:0005179]  
  • IEAUniProtKB KW
Hormone bindingdefinition[GO:0042562] silver  
  • IEAOrtholog Compara
Identical protein bindingdefinition[GO:0042802]  
4
  • IPIIntAct
Protein bindingdefinition[GO:0005515]  
3
  • IPIIntAct
  • IPIAgBase
Protein heterodimerization activitydefinition[GO:0046982] silver  
  • IEAOrtholog Compara
GO biological process 
Retinol metabolic processdefinition[GO:0042572] silver  
  • IEAOrtholog Compara
Transportdefinition[GO:0006810]  
  • IEAUniProtKB KW
Pathways 
According to Reactome, this protein belongs to the following pathways:
Amyloids  REACT_75925  
Non-integrin membrane-ECM interactions  REACT_163874  
Retinoid cycle disease events  REACT_160130  
Retinoid metabolism and transport  REACT_24968  
The canonical retinoid cycle in rods (twilight vision)  REACT_160156  
 

Keywords

Biological process 
Transport  definition   [KW-0813]
Molecular function 
Hormone  definition   [KW-0372]
Thyroid hormone  definition   [KW-0795]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: Transthyretin
GenomeRNAi: 7276
PRO: PR:P02766