CD3D - T-cell surface glycoprotein CD3 delta chain - human protein (Function)
 
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CD3D »  T-cell surface glycoprotein CD3 delta chain
 
Protein also known as:  T-cell receptor T3 delta chain; CD antigen CD3d.
Gene name:  CD3D
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 38 2
GENE REF ISO

Function

 show evidences
Overview 
The CD3 complex mediates signal transduction.  
  • CuratedUniProtKB
GO molecular function 
Protein heterodimerization activitydefinition[GO:0046982]  
1
  • IPIUniProtKB
Transcription coactivator activitydefinition[GO:0003713]  
1
  • IDAMGI
Transmembrane signaling receptor activitydefinition[GO:0004888]  
1
  • ICUniProtKB
GO biological process 
Cell surface receptor signaling pathwaydefinition[GO:0007166]  
1
  • ICUniProtKB
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944]  
1
  • IDAMGI
Positive thymic T cell selectiondefinition[GO:0045059]  
  • ISSOrtholog Curator
T cell differentiationdefinition[GO:0030217]  
1
  • IDAMGI
Pathways 
According to KEGG, this protein belongs to the following pathways:
Chagas disease (American trypanosomiasis)  hsa05142+915  
Hematopoietic cell lineage  hsa04640+915  
HTLV-I infection  hsa05166+915  
Measles  hsa05162+915  
Primary immunodeficiency  hsa05340+915  
T cell receptor signaling pathway  hsa04660+915  
According to Reactome, this protein belongs to the following pathway:
Immune System  REACT_6900  
 

Keywords

Molecular function 
Receptor  definition   [KW-0675]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: CD3D
GenomeRNAi: 915
PRO: PR:P04234