ASL - Argininosuccinate lyase - human protein (Function)
 
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Protein
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References

 
ASL »  Argininosuccinate lyase   [ EC 4.3.2.1 ]  (ASAL)
 
Protein also known as:  Arginosuccinase.
Gene name:  ASL
Entry whose protein(s) existence is based on evidence at protein level
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1 32 3
GENE REF ISO

Function

 show evidences
GO biological process 
Arginine biosynthetic process via ornithinedefinition[GO:0042450] silver  
  • IEAInterPro 2 GO
Arginine catabolic processdefinition[GO:0006527]  
1
  • TASPINC
Internal protein amino acid acetylationdefinition[GO:0006475]  
1
  • IDAUniProtKB
Urea cycledefinition[GO:0000050]  
  • IEAUniPathway
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 4.3.2.1: 2-(N(omega)-L-arginino)succinate fumarate + L-arginine.  
  • CuratedUniProtKB
It is regulated in the following manner
Enzyme activity is regulated by acetylation (By similarity).  
1
  • CuratedUniProtKB
Pathways 
This protein is involved in the following pathways
According to KEGG, this protein belongs to the following pathways:
Alanine, aspartate and glutamate metabolism  hsa00250+435  
Arginine and proline metabolism  hsa00330+435  
Metabolic pathways  hsa01100+435  
According to Reactome, this protein belongs to the following pathway:
Metabolism  REACT_111217  
 
More information is available from:
 

Keywords

Biological process 
Amino-acid biosynthesis  definition   [KW-0028]
Arginine biosynthesis  definition   [KW-0055]
Urea cycle  definition   [KW-0835]
Molecular function 
Lyase  definition   [KW-0456]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Enzyme and pathway databases
SABIO-RK: P04424
Other
GenomeRNAi: 435
PRO: PR:P04424