SSB - Lupus La protein - human protein (Function)
 
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Protein
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References

 
SSB »  Lupus La protein
 
Protein also known as:  Sjoegren syndrome type B antigen (SS-B).
Gene name:  SSB
Entry whose protein(s) existence is based on evidence at protein level
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1 134 1
GENE REF ISO

Function

 show evidences
Overview 
Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation.  
2
  • CuratedUniProtKB
GO molecular function 
mRNA bindingdefinition[GO:0003729]  
1
  • TASPINC
Nucleotide bindingdefinition[GO:0000166] silver  
  • IEAInterPro 2 GO
Poly(A) RNA bindingdefinition[GO:0044822]  
2
  • IDAUniProtKB
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
tRNA bindingdefinition[GO:0000049]  
1
  • TASPINC
GO biological process 
Histone mRNA metabolic processdefinition[GO:0008334]  
1
  • TASPINC
tRNA modificationdefinition[GO:0006400]  
1
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathway:
Systemic lupus erythematosus  hsa05322+6741  
According to Reactome, this protein belongs to the following pathways:
RNA Polymerase III Abortive And Retractive Initiation  REACT_22339  
RNA Polymerase III Transcription Termination  REACT_63  
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: Sjogren_syndrome_antigen_B
GenomeRNAi: 6741
PRO: PR:P05455