KRT8 - Keratin, type II cytoskeletal 8 - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
KRT8 »  Keratin, type II cytoskeletal 8
 
Protein also known as:  Type-II keratin Kb8.
Gene name:  KRT8
Family name: Intermediate filament
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 164 2
GENE REF ISO

Function

 show evidences
Overview 
Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.  
1
  • CuratedUniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
12
  • IPIIntAct
  • IPIUniProtKB
  • IPIHGNC
Protein complex bindingdefinition[GO:0032403] silver  
  • IEAOrtholog Compara
Scaffold protein bindingdefinition[GO:0097110]  
1
  • IPIBHF-UCL
Structural molecule activitydefinition[GO:0005198] silver  
  • IEAInterPro 2 GO
GO biological process 
Cell differentiation involved in embryonic placenta developmentdefinition[GO:0060706] silver  
  • IEAOrtholog Compara
Extrinsic apoptotic signaling pathwaydefinition[GO:0097191] silver  
  • IEAOrtholog Compara
Hepatocyte apoptotic processdefinition[GO:0097284] silver  
  • IEAOrtholog Compara
Response to hydrostatic pressuredefinition[GO:0051599] silver  
  • IEAOrtholog Compara
Response to other organismdefinition[GO:0051707] silver  
  • IEAOrtholog Compara
Sarcomere organizationdefinition[GO:0045214] silver  
  • IEAOrtholog Compara
Tumor necrosis factor-mediated signaling pathwaydefinition[GO:0033209] silver  
  • IEAOrtholog Compara
Viral processdefinition[GO:0016032]  
  • IEAUniProtKB KW
Note 
There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).  
  • CuratedUniProtKB
 

Keywords

Biological process 
Host-virus interaction  definition   [KW-0945]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: Keratin_8
GenomeRNAi: 3856
PRO: PR:P05787