SFTPB - Pulmonary surfactant-associated protein B - human protein (Function)
 
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SFTPB »  Pulmonary surfactant-associated protein B
 
Gene name:  SFTPB
Entry whose protein(s) existence is based on evidence at protein level
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Function

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Overview 
Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.  
  • CuratedUniProtKB
GO biological process 
Organ morphogenesisdefinition[GO:0009887]  
1
  • TASPINC
Respiratory gaseous exchangedefinition[GO:0007585]  
  • IEAUniProtKB KW
Sphingolipid metabolic processdefinition[GO:0006665] silver  
  • IEAInterPro 2 GO
Note 
Pulmonary surfactant consists of 90% lipid and 10% protein. There are 4 surfactant-associated proteins: 2 collagenous, carbohydrate-binding glycoproteins (SP-A and SP-D) and 2 small hydrophobic proteins (SP-B and SP-C).  
  • CuratedUniProtKB
 

Keywords

Biological process 
Gaseous exchange  definition   [KW-0305]
Technical term 
Reference proteome  definition   [KW-1185]
 

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