CELA2A - Chymotrypsin-like elastase family member 2A - human protein (Function)
 
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CELA2A »  Chymotrypsin-like elastase family member 2A   [ EC 3.4.21.71 ]
 
Protein also known as:  Elastase-2A.
Gene name:  CELA2A
Family name: Peptidase S1 » Elastase
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Acts upon elastin.  
  • CuratedUniProtKB
GO molecular function 
Serine hydrolase activitydefinition[GO:0017171]  
1
  • IDAMGI
Serine-type endopeptidase activitydefinition[GO:0004252] silver  
  • IEAInterPro 2 GO
GO biological process 
Proteolysisdefinition[GO:0006508]  
  • IEAUniProtKB KW
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 3.4.21.71: Preferential cleavage: Leu-|-Xaa, Met-|-Xaa and Phe-|-Xaa. Hydrolyzes elastin.  
  • CuratedUniProtKB
 
More information is available from:
Pathways 
According to KEGG, this protein belongs to the following pathways:
Pancreatic secretion  hsa04972+63036  
Protein digestion and absorption  hsa04974+63036  
 

Keywords

Molecular function 
Hydrolase  definition   [KW-0378]
Protease  definition   [KW-0645]
Serine protease  definition   [KW-0720]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: CELA2A
GenomeRNAi: 63036
PRO: PR:P08217