MYL3 - Myosin light chain 3 - human protein (Function)
 
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MYL3 »  Myosin light chain 3
 
Protein also known as:  Myosin light chain 1, slow-twitch muscle B/ventricular isoform (MLC1SB).
Gene name:  MYL3
Entry whose protein(s) existence is based on evidence at protein level
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1 21 1
GENE REF ISO

Function

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Overview 
Regulatory light chain of myosin. Does not bind calcium.  
  • CuratedUniProtKB
GO molecular function 
Actin monomer bindingdefinition[GO:0003785]  
1
  • IDABHF-UCL
Calcium ion bindingdefinition[GO:0005509] silver  
  • IEAInterPro 2 GO
Motor activitydefinition[GO:0003774] silver  
  • IEAOrtholog Compara
Myosin II heavy chain bindingdefinition[GO:0032038]  
1
  • NASBHF-UCL
Structural constituent of muscledefinition[GO:0008307]  
1
  • TASPINC
GO biological process 
Cardiac muscle contractiondefinition[GO:0060048]  
1
  • IMPBHF-UCL
Metabolic processdefinition[GO:0008152]  
  • IEAOrtholog Compara
Positive regulation of ATPase activitydefinition[GO:0032781]  
1
  • ISSBHF-UCL
Regulation of striated muscle contractiondefinition[GO:0006942]  
1
  • IMPBHF-UCL
Regulation of the force of heart contractiondefinition[GO:0002026]  
1
  • IMPBHF-UCL
Skeletal muscle tissue developmentdefinition[GO:0007519] silver  
  • IEAOrtholog Compara
Ventricular cardiac muscle tissue morphogenesisdefinition[GO:0055010]  
2
  • IMPBHF-UCL
Pathways 
According to KEGG, this protein belongs to the following pathways:
Cardiac muscle contraction  hsa04260+4634  
Dilated cardiomyopathy  hsa05414+4634  
Hypertrophic cardiomyopathy (HCM)  hsa05410+4634  
According to Reactome, this protein belongs to the following pathway:
Striated Muscle Contraction  REACT_16969  
 

Keywords

Molecular function 
Motor protein  definition   [KW-0505]
Muscle protein  definition   [KW-0514]
Myosin  definition   [KW-0518]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: MYL3
GenomeRNAi: 4634
PRO: PR:P08590