VIM - Vimentin - human protein (Function)
 
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Protein
Gene
References

 
VIM »  Vimentin
 
Gene name:  VIM
Family name: Intermediate filament
Entry whose protein(s) existence is based on evidence at protein level
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1 252 1
GENE REF ISO

Function

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Overview 
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.  
1
  • CuratedUniProtKB
Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.  
1
  • CuratedUniProtKB
GO molecular function 
Double-stranded RNA bindingdefinition[GO:0003725]  
1
  • IDAMGI
Identical protein bindingdefinition[GO:0042802]  
3
  • IPIIntAct
Protein bindingdefinition[GO:0005515]  
12
  • IPIIntAct
  • IPIUniProtKB
Protein C-terminus bindingdefinition[GO:0008022]  
1
  • IPIUniProtKB
Scaffold protein bindingdefinition[GO:0097110]  
1
  • IPIBHF-UCL
Structural constituent of cytoskeletondefinition[GO:0005200]  
1
  • IDAUniProtKB
Structural constituent of eye lensdefinition[GO:0005212] silver  
  • IEAOrtholog Compara
GO biological process 
Astrocyte developmentdefinition[GO:0014002] silver  
  • IEAOrtholog Compara
Bergmann glial cell differentiationdefinition[GO:0060020] silver  
  • IEAOrtholog Compara
Cellular component movementdefinition[GO:0006928]  
1
  • TASUniProtKB
Intermediate filament organizationdefinition[GO:0045109] silver  
  • IEAOrtholog Compara
Lens fiber cell developmentdefinition[GO:0070307] silver  
  • IEAOrtholog Compara
Negative regulation of neuron projection developmentdefinition[GO:0010977] silver  
  • IEAOrtholog Compara
Viral processdefinition[GO:0016032]  
  • IEAUniProtKB KW
Pathways 
According to Reactome, this protein belongs to the following pathways:
Apoptosis  REACT_578  
Muscle contraction  REACT_17044  
 

Keywords

Biological process 
Host-virus interaction  definition   [KW-0945]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: Vimentin
GenomeRNAi: 7431
PRO: PR:P08670