MYL2 - Myosin regulatory light chain 2, ventricular/cardiac muscle isoform - human protein (Function)
 
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MYL2 »  Myosin regulatory light chain 2, ventricular/cardiac muscle isoform  (MLC-2)
 
Gene name:  MYL2
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 47 1
GENE REF ISO

Function

 show evidences
GO molecular function 
Actin monomer bindingdefinition[GO:0003785]  
1
  • IDABHF-UCL
Calcium ion bindingdefinition[GO:0005509]  
1
  • IDAMGI
Myosin heavy chain bindingdefinition[GO:0032036]  
1
  • NASBHF-UCL
Protein bindingdefinition[GO:0005515]  
2
  • IPIIntAct
  • IPIUniProtKB
Structural constituent of muscledefinition[GO:0008307]  
1
  • NASBHF-UCL
GO biological process 
Cardiac muscle contractiondefinition[GO:0060048] silver  
  • IEAOrtholog Compara
Cardiac myofibril assemblydefinition[GO:0055003]  
  • ISSOrtholog Curator
Heart contractiondefinition[GO:0060047]  
  • ISSOrtholog Curator
Muscle cell fate specificationdefinition[GO:0042694] silver  
  • IEAOrtholog Compara
Muscle fiber developmentdefinition[GO:0048747] silver  
  • IEAOrtholog Compara
Negative regulation of cell growthdefinition[GO:0030308]  
1
  • IMPBHF-UCL
Post-embryonic developmentdefinition[GO:0009791] silver  
  • IEAOrtholog Compara
Regulation of striated muscle contractiondefinition[GO:0006942]  
1
  • TASPINC
Ventricular cardiac muscle tissue morphogenesisdefinition[GO:0055010]  
1
  • IMPBHF-UCL
Pathways 
According to KEGG, this protein belongs to the following pathways:
Cardiac muscle contraction  hsa04260+4633  
Dilated cardiomyopathy  hsa05414+4633  
Focal adhesion  hsa04510+4633  
Hypertrophic cardiomyopathy (HCM)  hsa05410+4633  
Leukocyte transendothelial migration  hsa04670+4633  
Regulation of actin cytoskeleton  hsa04810+4633  
Tight junction  hsa04530+4633  
According to Reactome, this protein belongs to the following pathway:
Muscle contraction  REACT_17044  
 

Keywords

Molecular function 
Motor protein  definition   [KW-0505]
Muscle protein  definition   [KW-0514]
Myosin  definition   [KW-0518]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: MYL2
GenomeRNAi: 4633
PRO: PR:P10916