LAMP1 - Lysosome-associated membrane glycoprotein 1 - human protein (Function)
 
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LAMP1 »  Lysosome-associated membrane glycoprotein 1  (LAMP-1)
 
Protein also known as:  CD107 antigen-like family member A; CD antigen CD107a.
Gene name:  LAMP1
Family name: LAMP
Entry whose protein(s) existence is based on evidence at protein level
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1 69 1
GENE REF ISO

Function

 show evidences
Overview 
Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the lysosomal protein import (lpi) family  9.A.16.1.1  
GO molecular function 
Enzyme bindingdefinition[GO:0019899]  
1
  • IPIUniProtKB
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
GO biological process 
Autophagic cell deathdefinition[GO:0048102] silver  
  • IEAOrtholog Compara
Autophagydefinition[GO:0006914] silver  
  • IEAOrtholog Compara
Establishment of protein localization to organelledefinition[GO:0072594]  
1
  • IMPUniProtKB
Golgi to lysosome transportdefinition[GO:0090160]  
1
  • IMPUniProtKB
Granzyme-mediated apoptotic signaling pathwaydefinition[GO:0008626]  
1
  • IMPUniProtKB
Positive regulation of natural killer cell degranulationdefinition[GO:0043323]  
1
  • IMPUniProtKB
Positive regulation of natural killer cell mediated cytotoxicitydefinition[GO:0045954]  
1
  • IMPUniProtKB
Protein stabilizationdefinition[GO:0050821]  
  • ISSOrtholog Curator
Regulation of organelle transport along microtubuledefinition[GO:1902513]  
1
  • IMPUniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathways:
Lysosome  hsa04142+3916  
Phagosome  hsa04145+3916  
Tuberculosis  hsa05152+3916  
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: LAMP1
GenomeRNAi: 3916
PRO: PR:P11279