COL11A1 - Collagen alpha-1(XI) chain - human protein (Function)
 
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COL11A1 »  Collagen alpha-1(XI) chain
 
Gene name:  COL11A1
Family name: Fibrillar collagen
Entry whose protein(s) existence is based on evidence at protein level
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1 71 4
GENE REF ISO

Function

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Overview 
May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils.  
1
  • UniProtKB
GO molecular function 
Extracellular matrix bindingdefinition[GO:0050840]  
1
  • UniProtKB
Extracellular matrix structural constituentdefinition[GO:0005201]  
1
  • UniProtKB
Metal ion bindingdefinition[GO:0046872]  
1
  • UniProtKB KW
Protein binding, bridgingdefinition[GO:0030674]  
1
  • UniProtKB
GO biological process 
Cartilage condensationdefinition[GO:0001502] silver  
1
  • Ortholog Compara
Chondrocyte developmentdefinition[GO:0002063] silver  
1
  • Ortholog Compara
Collagen fibril organizationdefinition[GO:0030199]  
1
  • UniProtKB
Detection of mechanical stimulus involved in sensory perception of sounddefinition[GO:0050910]  
1
  • UniProtKB
Embryonic skeletal system morphogenesisdefinition[GO:0048704] silver  
1
  • Ortholog Compara
Endodermal cell differentiationdefinition[GO:0035987]  
1
  • UniProtKB
Extracellular matrix organizationdefinition[GO:0030198]  
1
  • UniProtKB
Inner ear morphogenesisdefinition[GO:0042472] silver  
1
  • Ortholog Compara
Ossificationdefinition[GO:0001503] silver  
1
  • Ortholog Compara
Proteoglycan metabolic processdefinition[GO:0006029] silver  
1
  • Ortholog Compara
Sensory perception of sounddefinition[GO:0007605]  
1
  • UniProtKB
Tendon developmentdefinition[GO:0035989] silver  
1
  • Ortholog Compara
Ventricular cardiac muscle tissue morphogenesisdefinition[GO:0055010] silver  
1
  • Ortholog Compara
Visual perceptiondefinition[GO:0007601]  
2
  • UniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathways:
Amoebiasis  hsa05146+1301  
ECM-receptor interaction  hsa04512+1301  
Focal adhesion  hsa04510+1301  
Protein digestion and absorption  hsa04974+1301  
According to Reactome, this protein belongs to the following pathways:
Assembly of collagen fibrils and other multimeric structures  REACT_150180  
Collagen biosynthesis and modifying enzymes  REACT_121139  
Collagen degradation  REACT_150401  
Non-integrin membrane-ECM interactions  REACT_163874  
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: Collagen,_type_XI,_alpha_1
GenomeRNAi: 1301
PRO: PR:P12107