NCAM1 - Neural cell adhesion molecule 1 - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Protein
Gene
References

 
NCAM1 »  Neural cell adhesion molecule 1  (NCAM-1)
 
Protein also known as:  CD antigen CD56.
Gene name:  NCAM1
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 216 6
GENE REF ISO

Function

 show evidences
Overview 
This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.  
1
  • UniProtKB
(Microbial infection) Acts as a receptor for rabies virus.  
2
  • UniProtKB
GO molecular function 
Isoform  Iso 2   Identical protein bindingdefinition[GO:0042802]  
1
  • IntAct
Virus receptor activitydefinition[GO:0001618]  
1
  • UniProtKB KW
GO biological process 
Cell adhesiondefinition[GO:0007155]  
1
  • UniProtKB KW
Viral entry into host celldefinition[GO:0046718]  
1
  • UniProtKB KW
Pathways 
According to KEGG, this protein belongs to the following pathways:
Cell adhesion molecules (CAMs)  hsa04514+4684  
Prion diseases  hsa05020+4684  
According to Reactome, this protein belongs to the following pathways:
ECM proteoglycans  R-HSA-3000178  
Interferon gamma signaling  R-HSA-877300  
NCAM signaling for neurite out-growth  R-HSA-375165  
NCAM1 interactions  R-HSA-419037  
RAF/MAP kinase cascade  R-HSA-5673001  
Signal transduction by L1  R-HSA-445144  
 

Keywords

Biological process 
Cell adhesion  definition   [KW-0130]
Host-virus interaction  definition   [KW-0945]
Molecular function 
Host cell receptor for virus entry  definition   [KW-1183]
Receptor  definition   [KW-0675]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links