PDIA4 - Protein disulfide-isomerase A4 - human protein (Function)
 
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PDIA4 »  Protein disulfide-isomerase A4   [ EC 5.3.4.1 ]
 
Protein also known as:  Endoplasmic reticulum resident protein 70 (ERp70).
Gene name:  PDIA4
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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GO molecular function 
Poly(A) RNA bindingdefinition[GO:0044822]  
1
  • IDAUniProtKB
Protein bindingdefinition[GO:0005515]  
2
  • IPIIntAct
Protein disulfide isomerase activitydefinition[GO:0003756]  
  • ISSOrtholog Curator
  • IBARefGenome
Protein disulfide oxidoreductase activitydefinition[GO:0015035] silver  
  • IEAInterPro 2 GO
GO biological process 
Cell redox homeostasisdefinition[GO:0045454] silver  
  • IEAInterPro 2 GO
Chaperone-mediated protein foldingdefinition[GO:0061077]  
  • ISSOrtholog Curator
Glycerol ether metabolic processdefinition[GO:0006662] silver  
  • IEAInterPro 2 GO
Protein foldingdefinition[GO:0006457] silver  
  • IBARefGenome
Protein secretiondefinition[GO:0009306]  
1
  • TASPINC
Response to endoplasmic reticulum stressdefinition[GO:0034976] silver  
  • IBARefGenome
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 5.3.4.1: Catalyzes the rearrangement of -S-S- bonds in proteins.  
  • CuratedUniProtKB
 
More information is available from:
Pathways 
According to KEGG, this protein belongs to the following pathways:
Protein processing in endoplasmic reticulum  hsa04141+9601  
Vibrio cholerae infection  hsa05110+9601  
Caution 
Was originally (PubMed2549034) thought to be a deoxycytidine kinase.  
1
  • CuratedUniProtKB
 

Keywords

Molecular function 
Isomerase  definition   [KW-0413]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 9601
PRO: PR:P13667