COL11A2 - Collagen alpha-2(XI) chain - human protein (Function)
 
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COL11A2 »  Collagen alpha-2(XI) chain
 
Gene name:  COL11A2
Family name: Fibrillar collagen
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils.  
1
  • UniProtKB
GO molecular function 
Extracellular matrix structural constituent conferring tensile strengthdefinition[GO:0030020]  
2
  • UniProtKB
Metal ion bindingdefinition[GO:0046872]  
1
  • UniProtKB KW
Protein bindingdefinition[GO:0005515]  
1
  • IntAct
Protein binding, bridgingdefinition[GO:0030674]  
1
  • UniProtKB
GO biological process 
Cartilage developmentdefinition[GO:0051216]  
1
  • UniProtKB
Collagen fibril organizationdefinition[GO:0030199]  
1
  • UniProtKB
Palate developmentdefinition[GO:0060021]  
1
  • UniProtKB
Sensory perception of sounddefinition[GO:0007605]  
4
  • UniProtKB
  • MGI
Skeletal system developmentdefinition[GO:0001501]  
3
  • UniProtKB
Soft palate developmentdefinition[GO:0060023]  
1
  • UniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathways:
Amoebiasis  hsa05146+1302  
ECM-receptor interaction  hsa04512+1302  
Focal adhesion  hsa04510+1302  
Protein digestion and absorption  hsa04974+1302  
According to Reactome, this protein belongs to the following pathways:
Assembly of collagen fibrils and other multimeric structures  REACT_150180  
Collagen biosynthesis and modifying enzymes  REACT_121139  
Collagen degradation  REACT_150401  
Non-integrin membrane-ECM interactions  REACT_163874  
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: COL11A2_(gene)
GenomeRNAi: 1302
PRO: PR:P13942