GFAP - Glial fibrillary acidic protein - human protein (Function)
 
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GFAP »  Glial fibrillary acidic protein  (GFAP)
 
Gene name:  GFAP
Family name: Intermediate filament
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.  
  • CuratedUniProtKB
GO molecular function 
Integrin bindingdefinition[GO:0005178] silver  
  • IEAOrtholog Compara
Kinase bindingdefinition[GO:0019900] silver  
  • IEAOrtholog Compara
Structural constituent of cytoskeletondefinition[GO:0005200] silver  
  • IEAOrtholog Compara
GO biological process 
Astrocyte developmentdefinition[GO:0014002] silver  
  • IEAOrtholog Compara
Bergmann glial cell differentiationdefinition[GO:0060020] silver  
  • IEAOrtholog Compara
Extracellular matrix organizationdefinition[GO:0030198] silver  
  • IEAOrtholog Compara
Intermediate filament organizationdefinition[GO:0045109] silver  
  • IEAOrtholog Compara
Long-term synaptic potentiationdefinition[GO:0060291] silver  
  • IEAOrtholog Compara
Negative regulation of neuron projection developmentdefinition[GO:0010977] silver  
  • IEAOrtholog Compara
Neuron projection regenerationdefinition[GO:0031102] silver  
  • IEAOrtholog Compara
Positive regulation of Schwann cell proliferationdefinition[GO:0010625] silver  
  • IEAOrtholog Compara
Regulation of neurotransmitter uptakedefinition[GO:0051580] silver  
  • IEAOrtholog Compara
Response to woundingdefinition[GO:0009611] silver  
  • IEAOrtholog Compara
Pathways 
According to Reactome, this protein belongs to the following pathway:
Signal Transduction  REACT_111102  
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links