CD99 - CD99 antigen - human protein (Function)
 
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CD99 »  CD99 antigen
 
Protein also known as:  T-cell surface glycoprotein E2; CD antigen CD99.
Gene name:  CD99
Family name: CD99
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Involved in T-cell adhesion processes (By similarity).  
  • CuratedUniProtKB
GO biological process 
Cell adhesiondefinition[GO:0007155]  
  • IEAUniProtKB KW
Pathways 
According to KEGG, this protein belongs to the following pathways:
Cell adhesion molecules (CAMs)  hsa04514+4267  
Leukocyte transendothelial migration  hsa04670+4267  
Note 
The gene coding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.  
  • CuratedUniProtKB
 

Keywords

Biological process 
Cell adhesion  definition   [KW-0130]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: CD99
GenomeRNAi: 4267
PRO: PR:P14209