CPB1 - Carboxypeptidase B - human protein (Function)
 
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Protein
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CPB1 »  Carboxypeptidase B   [ EC 3.4.17.2 ]
 
Protein also known as:  Pancreas-specific protein (PASP).
Gene name:  CPB1
Family name: Peptidase M14
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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GO molecular function 
Carboxypeptidase activitydefinition[GO:0004180]  
1
  • TASPINC
Metallocarboxypeptidase activitydefinition[GO:0004181] silver  
  • IEAInterPro 2 GO
Zinc ion bindingdefinition[GO:0008270] silver  
  • IEAInterPro 2 GO
GO biological process 
Proteolysisdefinition[GO:0006508]  
  • IEAUniProtKB KW
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 3.4.17.2: Preferential release of a C-terminal lysine or arginine amino acid.  
  • CuratedUniProtKB
It requires the following cofactor
Binds 1 zinc ion per subunit.  
  • CuratedUniProtKB
 
More information is available from:
Pathways 
According to KEGG, this protein belongs to the following pathways:
Pancreatic secretion  hsa04972+1360  
Protein digestion and absorption  hsa04974+1360  
According to Reactome, this protein belongs to the following pathway:
Metabolism of Angiotensinogen to Angiotensins  REACT_147707  
 

Keywords

Molecular function 
Carboxypeptidase  definition   [KW-0121]
Hydrolase  definition   [KW-0378]
Metalloprotease  definition   [KW-0482]
Protease  definition   [KW-0645]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 1360
PRO: PR:P15086