CD1E - T-cell surface glycoprotein CD1e, membrane-associated - human protein (Function)
 
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CD1E »  T-cell surface glycoprotein CD1e, membrane-associated
 
Protein also known as:  R2G1; CD antigen CD1e. Cleaved into:  T-cell surface glycoprotein CD1e, soluble.
Gene name:  CD1E
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 37 13
GENE REF ISO

Function

 show evidences
Overview 
T-cell surface glycoprotein CD1e, soluble binds diacetylated lipids, including phosphatidyl inositides and diacylated sulfoglycolipids, and is required for the presentation of glycolipid antigens on the cell surface. The membrane-associated form is not active.  
3
  • CuratedUniProtKB
GO molecular function 
Beta-2-microglobulin bindingdefinition[GO:0030881] silver  
  • IBARefGenome
Endogenous lipid antigen bindingdefinition[GO:0030883] silver  
  • IBARefGenome
Exogenous lipid antigen bindingdefinition[GO:0030884] silver  
  • IBARefGenome
Lipopeptide bindingdefinition[GO:0071723] silver  
  • IBARefGenome
GO biological process 
Antigen processing and presentation, exogenous lipid antigen via MHC class Ibdefinition[GO:0048007] silver  
  • IBARefGenome
Immune responsedefinition[GO:0006955]  
1
  • NASUniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathway:
Hematopoietic cell lineage  hsa04640+913  
 

Keywords

Biological process 
Adaptive immunity  definition   [KW-1064]
Immunity  definition   [KW-0391]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: CD1E
GenomeRNAi: 913
PRO: PR:P15812