CD1D - Antigen-presenting glycoprotein CD1d - human protein (Function)
 
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CD1D »  Antigen-presenting glycoprotein CD1d
 
Protein also known as:  R3G1; CD antigen CD1d.
Gene name:  CD1D
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.  
2
  • UniProtKB
GO molecular function 
Beta-2-microglobulin bindingdefinition[GO:0030881]  
1
  • UniProtKB
Cell adhesion molecule bindingdefinition[GO:0050839]  
1
  • BHF-UCL
Endogenous lipid antigen bindingdefinition[GO:0030883]  
1
  • RefGenome
Exogenous lipid antigen bindingdefinition[GO:0030884]  
1
  • UniProtKB
Histone bindingdefinition[GO:0042393]  
1
  • UniProtKB
Lipid antigen bindingdefinition[GO:0030882]  
1
  • BHF-UCL
Lipopeptide bindingdefinition[GO:0071723]  
1
  • RefGenome
Receptor activitydefinition[GO:0004872]  
1
  • UniProtKB
GO biological process 
Antigen processing and presentation, endogenous lipid antigen via MHC class Ibdefinition[GO:0048006]  
1
  • UniProtKB
Antigen processing and presentation, exogenous lipid antigen via MHC class Ibdefinition[GO:0048007]  
1
  • RefGenome
Detection of bacteriumdefinition[GO:0016045]  
1
  • UniProtKB
Heterotypic cell-cell adhesiondefinition[GO:0034113]  
1
  • BHF-UCL
Innate immune responsedefinition[GO:0045087]  
1
  • UniProtKB KW
Positive regulation of innate immune responsedefinition[GO:0045089]  
1
  • UniProtKB
Positive regulation of T cell proliferationdefinition[GO:0042102]  
1
  • BHF-UCL
T cell selectiondefinition[GO:0045058]  
1
  • UniProtKB
Viral processdefinition[GO:0016032]  
1
  • UniProtKB KW
Pathways 
According to KEGG, this protein belongs to the following pathways:
Amoebiasis  hsa05146+912  
Hematopoietic cell lineage  hsa04640+912  
 

Keywords

Biological process 
Host-virus interaction  definition   [KW-0945]
Immunity  definition   [KW-0391]
Innate immunity  definition   [KW-0399]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: CD1D
GenomeRNAi: 912
PRO: PR:P15813