PAX1 - Paired box protein Pax-1 - human protein (Function)
 
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PAX1 »  Paired box protein Pax-1
 
Protein also known as:  HuP48.
Gene name:  PAX1
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
This protein is a transcriptional activator. It may play a role in the formation of segmented structures of the embryo. May play an important role in the normal development of the vertebral column (By similarity).  
  • CuratedUniProtKB
GO molecular function 
DNA bindingdefinition[GO:0003677]  
  • IEAUniProtKB KW
GO biological process 
Bone morphogenesisdefinition[GO:0060349] silver  
  • IEAOrtholog Compara
CD4-positive, alpha-beta T cell differentiationdefinition[GO:0043367] silver  
  • IEAOrtholog Compara
CD8-positive, alpha-beta T cell differentiationdefinition[GO:0043374] silver  
  • IEAOrtholog Compara
Cell proliferationdefinition[GO:0008283] silver  
  • IEAOrtholog Compara
Parathyroid gland developmentdefinition[GO:0060017] silver  
  • IEAOrtholog Compara
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944] silver  
  • IEAOrtholog Compara
Sclerotome developmentdefinition[GO:0061056] silver  
  • IEAOrtholog Compara
Skeletal system developmentdefinition[GO:0001501]  
1
  • TASPINC
Somitogenesisdefinition[GO:0001756] silver  
  • IEAOrtholog Compara
Thymus developmentdefinition[GO:0048538] silver  
  • IEAOrtholog Compara
Transcription from RNA polymerase II promoterdefinition[GO:0006366]  
1
  • TASPINC
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Activator  definition   [KW-0010]
Developmental protein  definition   [KW-0217]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: PAX1
GenomeRNAi: 5075
PRO: PR:P15863