ZNF24 - Zinc finger protein 24 - human protein (Function)
 
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ZNF24 »  Zinc finger protein 24
 
Protein also known as:  Zinc finger and SCAN domain-containing protein 3.
Gene name:  ZNF24
Entry whose protein(s) existence is based on evidence at protein level
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1 33 2
GENE REF ISO

Function

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Overview 
Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence (By similarity). Has transcription repressor activity in vitro.  
1
  • CuratedUniProtKB
GO molecular function 
DNA bindingdefinition[GO:0003677]  
1
  • TASPINC
Protein bindingdefinition[GO:0005515]  
3
  • IPIIntAct
Sequence-specific DNA bindingdefinition[GO:0043565]  
  • ISSOrtholog Curator
Sequence-specific DNA binding transcription factor activitydefinition[GO:0003700] silver  
  • IEAInterPro 2 GO
Zinc ion bindingdefinition[GO:0008270]  
1
  • NASUniProtKB
GO biological process 
Myelinationdefinition[GO:0042552]  
  • ISSOrtholog Curator
Negative regulation of transcription, DNA-templateddefinition[GO:0045892]  
1
  • IDAUniProtKB
Transcription, DNA-templateddefinition[GO:0006351]  
  • IEAUniProtKB KW
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Repressor  definition   [KW-0678]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ZNF24
GenomeRNAi: 7572
PRO: PR:P17028