JUNB - Transcription factor jun-B - human protein (Function)
 
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JUNB »  Transcription factor jun-B
 
Gene name:  JUNB
Family name: bZIP » Jun
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'.  
  • CuratedUniProtKB
GO molecular function 
DNA bindingdefinition[GO:0003677]  
1
  • TASPINC
Double-stranded DNA bindingdefinition[GO:0003690] silver  
  • IEAOrtholog Compara
Protein bindingdefinition[GO:0005515]  
4
  • IPIIntAct
RNA polymerase II regulatory region sequence-specific DNA bindingdefinition[GO:0000977] silver  
  • IEAOrtholog Compara
Sequence-specific DNA binding transcription factor activitydefinition[GO:0003700] silver  
  • IEAOrtholog Compara
Transcription coactivator activitydefinition[GO:0003713]  
1
  • TASPINC
Transcription corepressor activitydefinition[GO:0003714]  
1
  • TASPINC
GO biological process 
Cellular response to calcium iondefinition[GO:0071277] silver  
  • IEAOrtholog Compara
Cellular response to hormone stimulusdefinition[GO:0032870] silver  
  • IEAOrtholog Compara
Decidualizationdefinition[GO:0046697] silver  
  • IEAOrtholog Compara
Embryonic process involved in female pregnancydefinition[GO:0060136] silver  
  • IEAOrtholog Compara
Labyrinthine layer blood vessel developmentdefinition[GO:0060716] silver  
  • IEAOrtholog Compara
Osteoblast differentiationdefinition[GO:0001649] silver  
  • IEAOrtholog Compara
Osteoblast proliferationdefinition[GO:0033687] silver  
  • IEAOrtholog Compara
Osteoclast differentiationdefinition[GO:0030316] silver  
  • IEAOrtholog Compara
Positive regulation of cell differentiationdefinition[GO:0045597] silver  
  • IEAOrtholog Compara
Regulation of cell cycledefinition[GO:0051726] silver  
  • IEAOrtholog Compara
Regulation of transcription from RNA polymerase II promoterdefinition[GO:0006357]  
1
  • TASPINC
Response to cAMPdefinition[GO:0051591] silver  
  • IEAOrtholog Compara
Response to corticosteronedefinition[GO:0051412] silver  
  • IEAOrtholog Compara
Response to cytokinedefinition[GO:0034097] silver  
  • IEAOrtholog Compara
Response to drugdefinition[GO:0042493] silver  
  • IEAOrtholog Compara
Response to light stimulusdefinition[GO:0009416] silver  
  • IEAOrtholog Compara
Response to mechanical stimulusdefinition[GO:0009612] silver  
  • IEAOrtholog Compara
Response to peptide hormonedefinition[GO:0043434] silver  
  • IEAOrtholog Compara
Response to progesteronedefinition[GO:0032570] silver  
  • IEAOrtholog Compara
Trophectodermal cell differentiationdefinition[GO:0001829] silver  
  • IEAOrtholog Compara
Vasculogenesisdefinition[GO:0001570] silver  
  • IEAOrtholog Compara
Pathways 
According to KEGG, this protein belongs to the following pathway:
Osteoclast differentiation  hsa04380+3726  
According to Reactome, this protein belongs to the following pathways:
Disease  REACT_116125  
Gene Expression  REACT_71  
Signal Transduction  REACT_111102  
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: JUNB
GenomeRNAi: 3726
PRO: PR:P17275