SYN1 - Synapsin-1 - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Protein
Gene
References

 
SYN1 »  Synapsin-1
 
Protein also known as:  Brain protein 4.1.
Gene name:  SYN1
Family name: Synapsin
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 36 2
GENE REF ISO

Function

 show evidences
Overview 
Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.  
1
  • UniProtKB
GO molecular function 
Actin bindingdefinition[GO:0003779]  
1
  • UniProtKB KW
ATP bindingdefinition[GO:0005524]  
1
  • ParkinsonsUK-UCL
Calcium-dependent protein bindingdefinition[GO:0048306] silver  
1
  • Ortholog Compara
Catalytic activitydefinition[GO:0003824] silver  
1
  • InterPro 2 GO
Protein bindingdefinition[GO:0005515]  
1
  • IntAct
Protein kinase bindingdefinition[GO:0019901]  
1
  • Ortholog Curator
Transporter activitydefinition[GO:0005215]  
1
  • PINC
GO biological process 
Metabolic processdefinition[GO:0008152]  
1
  • InterPro 2 GO
Neurotransmitter secretiondefinition[GO:0007269] silver  
1
  • InterPro 2 GO
Regulation of neurotransmitter secretiondefinition[GO:0046928]  
1
  • ParkinsonsUK-UCL
Regulation of synaptic vesicle exocytosisdefinition[GO:2000300]  
1
  • ParkinsonsUK-UCL
Synaptic transmissiondefinition[GO:0007268]  
1
  • PINC
Pathways 
According to Reactome, this protein belongs to the following pathways:
Dopamine Neurotransmitter Release Cycle  REACT_15293  
Serotonin Neurotransmitter Release Cycle  REACT_15425  
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: Synapsin_I
GenomeRNAi: 6853
PRO: PR:P17600