SYN1 - Synapsin-1 - human protein (Function)
 
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SYN1 »  Synapsin-1
 
Protein also known as:  Brain protein 4.1.
Gene name:  SYN1
Family name: Synapsin
Entry whose protein(s) existence is based on evidence at protein level
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1 29 2
GENE REF ISO

Function

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Overview 
Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.  
  • CuratedUniProtKB
GO molecular function 
Actin bindingdefinition[GO:0003779]  
  • IEAUniProtKB KW
ATP bindingdefinition[GO:0005524] silver  
  • IEAInterPro 2 GO
Calcium-dependent protein bindingdefinition[GO:0048306] silver  
  • IEAOrtholog Compara
Catalytic activitydefinition[GO:0003824] silver  
  • IEAInterPro 2 GO
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
Protein kinase bindingdefinition[GO:0019901]  
  • ISSOrtholog Curator
Transporter activitydefinition[GO:0005215]  
1
  • TASPINC
GO biological process 
Metabolic processdefinition[GO:0008152]  
  • IEAInterPro 2 GO
Neurotransmitter secretiondefinition[GO:0007269] silver  
  • IEAInterPro 2 GO
Synaptic transmissiondefinition[GO:0007268]  
1
  • TASPINC
Pathways 
According to Reactome, this protein belongs to the following pathways:
Dopamine Neurotransmitter Release Cycle  REACT_15293  
Serotonin Neurotransmitter Release Cycle  REACT_15425  
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: Synapsin_I
GenomeRNAi: 6853
PRO: PR:P17600