GNAT2 - Guanine nucleotide-binding protein G(t) subunit alpha-2 - human protein (Function)
 
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GNAT2 »  Guanine nucleotide-binding protein G(t) subunit alpha-2
 
Protein also known as:  Transducin alpha-2 chain.
Gene name:  GNAT2
Family name: G-alpha » G(i/o/t/z)
Entry whose protein(s) existence is based on evidence at protein level
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Function

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Overview 
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.  
1
  • UniProtKB
GO molecular function 
G-protein beta/gamma-subunit complex bindingdefinition[GO:0031683]  
1
  • RefGenome
G-protein coupled photoreceptor activitydefinition[GO:0008020]  
1
  • UniProtKB
G-protein coupled receptor bindingdefinition[GO:0001664]  
1
  • RefGenome
GTP bindingdefinition[GO:0005525]  
1
  • UniProtKB
GTPase activitydefinition[GO:0003924]  
1
  • RefGenome
Metal ion bindingdefinition[GO:0046872]  
1
  • UniProtKB KW
GO biological process 
Adenylate cyclase-modulating G-protein coupled receptor signaling pathwaydefinition[GO:0007188]  
1
  • RefGenome
Detection of chemical stimulus involved in sensory perception of bitter tastedefinition[GO:0001580]  
1
  • RefGenome
Detection of light stimulus involved in visual perceptiondefinition[GO:0050908]  
1
  • UniProtKB
G-protein coupled receptor signaling pathwaydefinition[GO:0007186]  
1
  • UniProtKB
Metabolic processdefinition[GO:0008152]  
2
  • InterPro 2 GO
  • RefGenome
Phototransductiondefinition[GO:0007602]  
1
  • UniProtKB
Positive regulation of cytosolic calcium ion concentrationdefinition[GO:0007204] silver  
1
  • Ortholog Compara
Response to light intensitydefinition[GO:0009642] silver  
1
  • Ortholog Compara
Retinal cone cell developmentdefinition[GO:0046549] silver  
1
  • Ortholog Compara
Visual perceptiondefinition[GO:0007601]  
1
  • UniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathway:
Phototransduction  hsa04744+2780  
According to Reactome, this protein belongs to the following pathways:
Ca2+ pathway  REACT_263982  
G alpha (i) signalling events  REACT_19231  
G-protein activation  REACT_15457  
PLC beta mediated events  REACT_15426  
 

Keywords

Biological process 
Sensory transduction  definition   [KW-0716]
Vision  definition   [KW-0844]
Molecular function 
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: GNAT2
GenomeRNAi: 2780
PRO: PR:P19087