PGC - Gastricsin - human protein (Function)
 
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PGC »  Gastricsin   [ EC 3.4.23.3 ]
 
Protein also known as:  Pepsinogen C.
Gene name:  PGC
Family name: Peptidase A1
Entry whose protein(s) existence is based on evidence at protein level
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1 39 2
GENE REF ISO

Function

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Overview 
Hydrolyzes a variety of proteins.  
  • CuratedUniProtKB
GO molecular function 
Aspartic-type endopeptidase activitydefinition[GO:0004190]  
  • IEAUniProtKB KW
GO biological process 
Digestiondefinition[GO:0007586]  
  • IEAUniProtKB KW
Proteolysisdefinition[GO:0006508]  
1
  • TASPINC
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 3.4.23.3: More restricted specificity than pepsin A, but shows preferential cleavage at Tyr-|-Xaa bonds. High activity on hemoglobin.  
  • CuratedUniProtKB
 
More information is available from:
 

Keywords

Biological process 
Digestion  definition   [KW-0222]
Molecular function 
Aspartyl protease  definition   [KW-0064]
Hydrolase  definition   [KW-0378]
Protease  definition   [KW-0645]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: Gastricsin
GenomeRNAi: 5225
PRO: PR:P20142