POU3F2 - POU domain, class 3, transcription factor 2 - human protein (Function)
 
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Protein
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POU3F2 »  POU domain, class 3, transcription factor 2
 
Protein also known as:  Nervous system-specific octamer-binding transcription factor N-Oct-3.
Gene name:  POU3F2
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 26 3
GENE REF ISO

Function

 show evidences
Overview 
Transcription factor that binds preferentially to the recognition sequence which consists of two distinct half-sites, ('GCAT') and ('TAAT'), separated by a nonconserved spacer region of 0, 2, or 3 nucleotides. Positively regulates the genes under the control of corticotropin-releasing hormone (CRH) and CRH II promoters (By similarity).  
  • CuratedUniProtKB
GO molecular function 
Identical protein bindingdefinition[GO:0042802]  
1
  • IPIIntAct
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
RNA polymerase II transcription coactivator activitydefinition[GO:0001105] silver  
  • IEAOrtholog Compara
Sequence-specific DNA bindingdefinition[GO:0043565] silver  
  • IEAOrtholog Compara
Sequence-specific DNA binding transcription factor activitydefinition[GO:0003700] silver  
  • IEAInterPro 2 GO
GO biological process 
Astrocyte developmentdefinition[GO:0014002] silver  
  • IEAOrtholog Compara
Cellular response to organic substancedefinition[GO:0071310] silver  
  • IEAOrtholog Compara
Cerebral cortex radially oriented cell migrationdefinition[GO:0021799] silver  
  • IEAOrtholog Compara
Epidermis developmentdefinition[GO:0008544] silver  
  • IEAOrtholog Compara
Forebrain ventricular zone progenitor cell divisiondefinition[GO:0021869] silver  
  • IEAOrtholog Compara
Hypothalamus cell differentiationdefinition[GO:0021979] silver  
  • IEAOrtholog Compara
Myelination in peripheral nervous systemdefinition[GO:0022011] silver  
  • IEAOrtholog Compara
Neurohypophysis developmentdefinition[GO:0021985] silver  
  • IEAOrtholog Compara
Neuron differentiationdefinition[GO:0030182] silver  
  • IEAOrtholog Compara
Positive regulation of cell proliferationdefinition[GO:0008284]  
1
  • IDAMGI
Positive regulation of multicellular organism growthdefinition[GO:0040018] silver  
  • IEAOrtholog Compara
Regulation of axonogenesisdefinition[GO:0050770] silver  
  • IEAOrtholog Compara
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Activator  definition   [KW-0010]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: POU3F2
GenomeRNAi: 5454
PRO: PR:P20265