HOXA5 - Homeobox protein Hox-A5 - human protein (Function)
 
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HOXA5 »  Homeobox protein Hox-A5
 
Protein also known as:  Homeobox protein Hox-1C.
Gene name:  HOXA5
Family name: Antp homeobox
Entry whose protein(s) existence is based on evidence at protein level
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1 39 1
GENE REF ISO

Function

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Overview 
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Also binds to its own promoter. Binds specifically to the motif 5'-CYYNATTA[TG]Y-3'.  
  • CuratedUniProtKB
GO molecular function 
DNA bindingdefinition[GO:0003677]  
1
  • IDAUniProtKB
Protein bindingdefinition[GO:0005515]  
1
  • IPIUniProtKB
Sequence-specific DNA bindingdefinition[GO:0043565] silver  
  • IEAInterPro 2 GO
Sequence-specific DNA binding transcription factor activitydefinition[GO:0003700]  
2
  • IDAUniProtKB
GO biological process 
Anterior/posterior pattern specificationdefinition[GO:0009952] silver  
  • IEAOrtholog Compara
Bronchiole developmentdefinition[GO:0060435] silver  
  • IEAOrtholog Compara
Cell migrationdefinition[GO:0016477] silver  
  • IEAOrtholog Compara
Cell-cell signaling involved in mammary gland developmentdefinition[GO:0060764] silver  
  • IEAOrtholog Compara
Embryonic skeletal system morphogenesisdefinition[GO:0048704] silver  
  • IEAOrtholog Compara
Epithelial tube branching involved in lung morphogenesisdefinition[GO:0060441] silver  
  • IEAOrtholog Compara
Intestinal epithelial cell maturationdefinition[GO:0060574] silver  
  • IEAOrtholog Compara
Lung alveolus developmentdefinition[GO:0048286] silver  
  • IEAOrtholog Compara
Lung goblet cell differentiationdefinition[GO:0060480] silver  
  • IEAOrtholog Compara
Lung-associated mesenchyme developmentdefinition[GO:0060484] silver  
  • IEAOrtholog Compara
Mammary gland alveolus developmentdefinition[GO:0060749] silver  
  • IEAOrtholog Compara
Mammary gland epithelial cell differentiationdefinition[GO:0060644] silver  
  • IEAOrtholog Compara
Mesenchymal-epithelial cell signalingdefinition[GO:0060638] silver  
  • IEAOrtholog Compara
Multicellular organism growthdefinition[GO:0035264] silver  
  • IEAOrtholog Compara
Negative regulation of angiogenesisdefinition[GO:0016525]  
1
  • IMPUniProtKB
Negative regulation of erythrocyte differentiationdefinition[GO:0045647]  
1
  • IDAUniProtKB
Positive regulation of apoptotic processdefinition[GO:0043065]  
1
  • IDAUniProtKB
Positive regulation of myeloid cell differentiationdefinition[GO:0045639]  
1
  • IDAUniProtKB
Positive regulation of receptor biosynthetic processdefinition[GO:0010870]  
1
  • IDAUniProtKB
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944]  
2
  • IDAUniProtKB
Regulation of mammary gland epithelial cell proliferationdefinition[GO:0033599] silver  
  • IEAOrtholog Compara
Respiratory system processdefinition[GO:0003016] silver  
  • IEAOrtholog Compara
Thyroid gland developmentdefinition[GO:0030878] silver  
  • IEAOrtholog Compara
Trachea cartilage morphogenesisdefinition[GO:0060535] silver  
  • IEAOrtholog Compara
Transcription, DNA-templateddefinition[GO:0006351]  
  • IEAUniProtKB KW
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Developmental protein  definition   [KW-0217]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: HOXA5
GenomeRNAi: 3202
PRO: PR:P20719