TNXB - Tenascin-X - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
TNXB »  Tenascin-X  (TN-X)
 
Protein also known as:  Hexabrachion-like protein.
Gene name:  TNXB
Family name: Tenascin
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 66 3
GENE REF ISO

Function

 show evidences
Overview 
Appears to mediate interactions between cells and the extracellular matrix. Substrate-adhesion molecule that appears to inhibit cell migration. Accelerates collagen fibril formation. May play a role in supporting the growth of epithelial tumors.  
1
  • CuratedUniProtKB
GO molecular function 
Collagen bindingdefinition[GO:0005518] silver  
  • IEAOrtholog Compara
Heparin bindingdefinition[GO:0008201]  
  • ISSOrtholog Curator
Integrin bindingdefinition[GO:0005178]  
  • ISSOrtholog Curator
GO biological process 
Actin cytoskeleton organizationdefinition[GO:0030036]  
  • ISSOrtholog Curator
Cell adhesiondefinition[GO:0007155]  
  • ISSOrtholog Curator
Cell-matrix adhesiondefinition[GO:0007160] silver  
  • IEAOrtholog Compara
Collagen fibril organizationdefinition[GO:0030199] silver  
  • IEAOrtholog Compara
Collagen metabolic processdefinition[GO:0032963]  
1
  • IMPUniProtKB
Elastic fiber assemblydefinition[GO:0048251]  
1
  • IMPUniProtKB
Extracellular fibril organizationdefinition[GO:0043206] silver  
  • IEAOrtholog Compara
Fatty acid metabolic processdefinition[GO:0006631] silver  
  • IEAOrtholog Compara
Regulation of JUN kinase activitydefinition[GO:0043506] silver  
  • IEAOrtholog Compara
Single organismal cell-cell adhesiondefinition[GO:0016337] silver  
  • IEAOrtholog Compara
Triglyceride metabolic processdefinition[GO:0006641] silver  
  • IEAOrtholog Compara
Pathways 
According to KEGG, this protein belongs to the following pathways:
ECM-receptor interaction  hsa04512+7148  
Focal adhesion  hsa04510+7148  
According to Reactome, this protein belongs to the following pathway:
ECM proteoglycans  REACT_163906  
Caution 
There are two genes for TN-X: TNXA and TNXB. TNXA is a partial gene which can sometimes recombine with TNXB.  
  • CuratedUniProtKB
 

Keywords

Biological process 
Cell adhesion  definition   [KW-0130]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: Tenascin_X
GenomeRNAi: 7148
PRO: PR:P22105