USF1 - Upstream stimulatory factor 1 - human protein (Function)
 
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Protein
Gene
References

 
USF1 »  Upstream stimulatory factor 1
 
Protein also known as:  Class B basic helix-loop-helix protein 11 (bHLHb11).
Gene name:  USF1
Entry whose protein(s) existence is based on evidence at protein level
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1 97 2
GENE REF ISO

Function

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Overview 
Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.  
  • CuratedUniProtKB
GO molecular function 
bHLH transcription factor bindingdefinition[GO:0043425]  
1
  • IPIBHF-UCL
Double-stranded DNA bindingdefinition[GO:0003690] silver  
  • IEAOrtholog Compara
Enzyme bindingdefinition[GO:0019899]  
1
  • IPIBHF-UCL
Histone deacetylase bindingdefinition[GO:0042826]  
1
  • IPIBHF-UCL
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
Protein heterodimerization activitydefinition[GO:0046982]  
1
  • IPIBHF-UCL
Protein homodimerization activitydefinition[GO:0042803]  
2
  • IPIBHF-UCL
Protein kinase bindingdefinition[GO:0019901]  
1
  • IPIBHF-UCL
RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activitydefinition[GO:0003705]  
3
  • IMPBHF-UCL
Sequence-specific DNA bindingdefinition[GO:0043565]  
2
  • IDABHF-UCL
GO biological process 
Carbon catabolite regulation of transcriptiondefinition[GO:0045990]  
1
  • TASBHF-UCL
Cellular response to insulin stimulusdefinition[GO:0032869]  
1
  • IDABHF-UCL
Glucose homeostasisdefinition[GO:0042593]  
1
  • TASBHF-UCL
Glucose metabolic processdefinition[GO:0006006] silver  
  • IEAOrtholog Compara
Late viral transcriptiondefinition[GO:0019086]  
1
  • IDABHF-UCL
Lipid homeostasisdefinition[GO:0055088]  
  • ISSOrtholog Curator
Negative regulation of fibrinolysisdefinition[GO:0051918]  
1
  • ICBHF-UCL
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944]  
2
  • IMPBHF-UCL
Positive regulation of transcription from RNA polymerase II promoter by glucosedefinition[GO:0000432]  
1
  • IMPBHF-UCL
  • ISSOrtholog Curator
Regulation of transcription from RNA polymerase II promoterdefinition[GO:0006357]  
1
  • TASBHF-UCL
Regulation of transcription from RNA polymerase II promoter by glucosedefinition[GO:0000430]  
1
  • ICBHF-UCL
Response to hypoxiadefinition[GO:0001666]  
1
  • IMPBHF-UCL
Response to UVdefinition[GO:0009411]  
  • ISSOrtholog Curator
Transcription from RNA polymerase II promoterdefinition[GO:0006366]  
1
  • IDABHF-UCL
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: USF1
GenomeRNAi: 7391
PRO: PR:P22415