KCNA4 - Potassium voltage-gated channel subfamily A member 4 - human protein (Function)
 
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Protein
Gene
References

 
KCNA4 »  Potassium voltage-gated channel subfamily A member 4
 
Protein also known as:  Voltage-gated potassium channel subunit Kv1.4.
Gene name:  KCNA4
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 37 1
GENE REF ISO

Function

 show evidences
Overview 
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.  
  • CuratedUniProtKB
GO molecular function 
Not  Delayed rectifier potassium channel activitydefinition[GO:0005251] silver  
  • IBARefGenome
Potassium ion bindingdefinition[GO:0030955] silver  
  • IEAInterPro 2 GO
Protein bindingdefinition[GO:0005515]  
3
  • IPIIntAct
  • IPIUniProtKB
Voltage-gated potassium channel activitydefinition[GO:0005249]  
1
  • TASPINC
GO biological process 
Potassium ion transmembrane transportdefinition[GO:0071805]  
  • IEAUniProtKB KW
Potassium ion transportdefinition[GO:0006813]  
1
  • TASPINC
Protein homooligomerizationdefinition[GO:0051260] silver  
  • IEAInterPro 2 GO
Regulation of ion transmembrane transportdefinition[GO:0034765]  
  • IEAUniProtKB KW
Pathways 
According to Reactome, this protein belongs to the following pathway:
Voltage gated Potassium channels  REACT_75770  
 

Keywords

Biological process 
Ion transport  definition   [KW-0406]
Potassium transport  definition   [KW-0633]
Transport  definition   [KW-0813]
Molecular function 
Ion channel  definition   [KW-0407]
Potassium channel  definition   [KW-0631]
Voltage-gated channel  definition   [KW-0851]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: KCNA4
GenomeRNAi: 3739
PRO: PR:P22459
Chemistry
GuidetoPHARMACOLOGY: 541