GNLY - Granulysin - human protein (Function)
 
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GNLY »  Granulysin
 
Protein also known as:  T-cell activation protein 519.
Gene name:  GNLY
Entry whose protein(s) existence is based on evidence at protein level
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1 45 2
GENE REF ISO

Function

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Overview 
Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis.  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the amoebapore (amoebapore) family  1.C.35.3.2  
GO biological process 
Cellular defense responsedefinition[GO:0006968]  
1
  • TASPINC
Defense response to bacteriumdefinition[GO:0042742]  
  • IEAUniProtKB KW
Defense response to fungusdefinition[GO:0050832]  
  • IEAUniProtKB KW
Killing of cells of other organismdefinition[GO:0031640]  
  • IEAUniProtKB KW
 

Keywords

Molecular function 
Antibiotic  definition   [KW-0044]
Antimicrobial  definition   [KW-0929]
Fungicide  definition   [KW-0295]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: GNLY
GenomeRNAi: 10578
PRO: PR:P22749