GLRA1 - Glycine receptor subunit alpha-1 - human protein (Sequence)
 
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GLRA1 »  Glycine receptor subunit alpha-1
 
Protein also known as:  Glycine receptor strychnine-binding subunit.
Gene name:  GLRA1
Entry whose protein(s) existence is based on evidence at protein level
extend overview
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GENE REF ISO

Displayed isoform: a     

 
 
Isoform a   457 aaMass: 52624 Da,  pI: 8.97
MYSFNTLRLY LWETIVFFSL AASKEAEAAR SAPKPMSPSD FLDKLMGRTS GYDARIRPNF KGPPVNVSCN IFINSFGSIA ETTMDYRVNI FLRQQWNDPR LAYNEYPDDS LDLDPSMLDS IWKPDLFFAN EKGAHFHEIT TDNKLLRISR NGNVLYSIRI TLTLACPMDL KNFPMDVQTC IMQLESFGYT MNDLIFEWQE QGAVQVADGL TLPQFILKEE KDLRYCTKHY NTGKFTCIEA RFHLERQMGY YLIQMYIPSL LIVILSWISF WINMDAAPAR VGLGITTVLT MTTQSSGSRA SLPKVSYVKA IDIWMAVCLL FVFSALLEYA AVNFVSRQHK ELLRFRRKRR HHKSPMLNLF QEDEAGEGRF NFSAYGMGPA CLQAKDGISV KGANNSNTTN PPPAPSKSPE EMRKLFIQRA KKIDKISRIG FPMAFLIFNM FYWIIYKIVR REDVHNQ

Keywords

Coding sequence diversity 
Alternative splicing  definition   [KW-0025]
Domain 
Signal  definition   [KW-0732]
Transmembrane  definition   [KW-0812]
Transmembrane helix  definition   [KW-1133]
PTM 
Disulfide bond  definition   [KW-1015]
Glycoprotein  definition   [KW-0325]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Family and domain databases
Gene3D: 2.70.170.10
InterPro: IPR006029 [ Neurotrans-gated channel TM ]
InterPro: IPR006028 [ GABAA/Glycine rcpt ]
InterPro: IPR008127 [ Glycine rcpt A ]
InterPro: IPR006202 [ Neur chan lig-bd ]
InterPro: IPR006201 [ Neur channel ]
InterPro: IPR018000 [ Neurotransmitter ion chnl CS ]
InterPro: IPR008128 [ Glycine rcpt A1 ]
PANTHER: PTHR18945 [ PTHR18945 ]
Pfam: PF02932 [ Neur chan memb ]
Pfam: PF02931 [ Neur chan LBD ]
PRINTS: PR00253 [ GABAARECEPTR ]
PRINTS: PR00252 [ NRIONCHANNEL ]
PRINTS: PR01673 [ GLYRALPHA ]
PRINTS: PR01674 [ GLYRALPHA1 ]
PROSITE: PS00236 [ NEUROTR ION CHANNEL ]
SUPFAM: SSF90112 [ SSF90112 ]
SUPFAM: SSF63712 [ SSF63712 ]
TIGRFAMs: TIGR00860 [ LIC ]
Genome annotation databases
Ensembl: Transcript: ENST00000274576;  Protein: ENSP00000274576;  Gene: ENSG00000145888.
Ensembl: Transcript: ENST00000462581;  Protein: ENSP00000430595;  Gene: ENSG00000145888.
Ensembl: Transcript: ENST00000455880;  Protein: ENSP00000411593;  Gene: ENSG00000145888.
Ensembl: Transcript: ENST00000545569;  Protein: ENSP00000445913;  Gene: ENSG00000145888.
KEGG: hsa:2741
UCSC: uc003lut.3
UCSC: uc003lur.3
Organism-specific databases
MGI: MGI:95747 [ Glra1 ]
Other
EvolutionaryTrace: P23415
PTM databases
PhosphoSite: P23415
Phylogenomic databases
eggNOG: NOG265706
HOGENOM: HOG000231336
HOVERGEN: HBG051707
InParanoid: P23415
KO: K05193
OMA: NTANPVP
OrthoDB: EOG712TVZ
PhylomeDB: P23415
Sequence databases
CCDS: CCDS4320.1 [ P23415-2 ]
CCDS: CCDS54942.1 [ P23415-1 ]
EMBL: Genomic DNA:  CH471062 . Translation:  EAW61657.1 .
EMBL: mRNA:  BC074980 . Translation:  AAH74980.1 .
EMBL: mRNA:  X52009 . Translation:  CAA36258.1 .
EMBL: mRNA:  BC114947 . Translation:  AAI14948.1 .
EMBL: mRNA:  AK312702 . Translation:  BAG35580.1 .
IPI: IPI00011565
IPI: IPI00795343
PIR: S12382
RefSeq: Protein:  NP_001139512.1. Nucleotide sequence:  NM_001146040.1.
RefSeq: Protein:  NP_000162.2. Nucleotide sequence:  NM_000171.3.
UniProtKB: P23415