ADRA1D - Alpha-1D adrenergic receptor - human protein (Function)
 
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ADRA1D »  Alpha-1D adrenergic receptor
 
Protein also known as:  Alpha-adrenergic receptor 1a.
Gene name:  ADRA1D
Entry whose protein(s) existence is based on evidence at transcript level
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1 37 1
GENE REF ISO

Function

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Overview 
This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.  
  • CuratedUniProtKB
GO molecular function 
Alpha1-adrenergic receptor activitydefinition[GO:0004937] silver  
  • IEAOrtholog Compara
GO biological process 
Adenylate cyclase-modulating G-protein coupled receptor signaling pathwaydefinition[GO:0007188]  
1
  • TASPINC
Adrenergic receptor signaling pathwaydefinition[GO:0071875]  
1
  • TASGOC
  • IEAOrtholog Compara
  • IEAInterPro 2 GO
Cell proliferationdefinition[GO:0008283]  
1
  • TASPINC
Cell-cell signalingdefinition[GO:0007267]  
1
  • TASPINC
DNA metabolic processdefinition[GO:0006259]  
1
  • TASPINC
G-protein coupled receptor signaling pathwaydefinition[GO:0007186]  
1
  • TASPINC
Multicellular organismal developmentdefinition[GO:0007275]  
1
  • TASPINC
Negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressuredefinition[GO:0001986] silver  
  • IEAOrtholog Compara
Norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressuredefinition[GO:0001994] silver  
  • IEAOrtholog Compara
Positive regulation of cell proliferationdefinition[GO:0008284]  
1
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathways:
Calcium signaling pathway  hsa04020+146  
Neuroactive ligand-receptor interaction  hsa04080+146  
Salivary secretion  hsa04970+146  
Vascular smooth muscle contraction  hsa04270+146  
According to Reactome, this protein belongs to the following pathways:
Adrenoceptors  REACT_16927  
G alpha (12/13) signalling events  REACT_18407  
G alpha (q) signalling events  REACT_18283  
 

Keywords

Molecular function 
G-protein coupled receptor  definition   [KW-0297]
Receptor  definition   [KW-0675]
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: Alpha-1D_adrenergic_receptor
GenomeRNAi: 146
PRO: PR:P25100
Chemistry
GuidetoPHARMACOLOGY: 24