CD27 - CD27 antigen - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
CD27 »  CD27 antigen
 
Protein also known as:  Tumor necrosis factor receptor superfamily member 7; CD antigen CD27.
Gene name:  CD27
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 71 1
GENE REF ISO

Function

 show evidences
Overview 
Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.  
  • CuratedUniProtKB
GO molecular function 
Cysteine-type endopeptidase inhibitor activity involved in apoptotic processdefinition[GO:0043027]  
1
  • IDAUniProtKB
Protein bindingdefinition[GO:0005515]  
3
  • IPIHGNC
  • IPIUniProtKB
  • IPIIntAct
Transmembrane signaling receptor activitydefinition[GO:0004888]  
1
  • NASUniProtKB
GO biological process 
Cell surface receptor signaling pathwaydefinition[GO:0007166]  
1
  • NASUniProtKB
Extrinsic apoptotic signaling pathwaydefinition[GO:0097191]  
1
  • IDABHF-UCL
Immunoglobulin mediated immune responsedefinition[GO:0016064]  
1
  • NASUniProtKB
Negative regulation of apoptotic processdefinition[GO:0043066]  
1
  • IDAUniProtKB
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic processdefinition[GO:0043154]  
1
  • IDAGOC
Negative regulation of T cell apoptotic processdefinition[GO:0070233] silver  
  • IEAOrtholog Compara
Positive regulation of B cell differentiationdefinition[GO:0045579]  
1
  • NASUniProtKB
Positive regulation of JNK cascadedefinition[GO:0046330]  
  • ISSOrtholog Curator
Release of cytoplasmic sequestered NF-kappaBdefinition[GO:0008588]  
1
  • NASUniProtKB
Response to ethanoldefinition[GO:0045471] silver  
  • IEAOrtholog Compara
Pathways 
According to KEGG, this protein belongs to the following pathway:
Cytokine-cytokine receptor interaction  hsa04060+939  
 

Keywords

Biological process 
Apoptosis  definition   [KW-0053]
Molecular function 
Receptor  definition   [KW-0675]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: CD27
GenomeRNAi: 939
PRO: PR:P26842
Chemistry
GuidetoPHARMACOLOGY: 1876