POU1F1 - Pituitary-specific positive transcription factor 1 - human protein (Sequence)
 
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Protein
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References

 
POU1F1 »  Pituitary-specific positive transcription factor 1  (PIT-1)
 
Protein also known as:  Growth hormone factor 1 (GHF-1).
Gene name:  POU1F1
Entry whose protein(s) existence is based on evidence at protein level
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1 77 2
GENE REF ISO

Displayed isoform: B     

 
 
Isoform B   291 aaMass: 32912 Da,  pI: 8.36
MSCQAFTSAD TFIPLNSDAS ATLPLIMHHS AAECLPVSNH ATNVMSTATG LHYSVPSCHY GNQPSTYGVM AGSLTPCLYK FPDHTLSHGF PPIHQPLLAE DPTAADFKQE LRRKSKLVEE PIDMDSPEIR ELEKFANEFK VRRIKLGYTQ TNVGEALAAV HGSEFSQTTI CRFENLQLSF KNACKLKAIL SKWLEEAEQV GALYNEKVGA NERKRKRRTT ISIAAKDALE RHFGEQNKPS SQEIMRMAEE LNLEKEVVRV WFCNRRQREK RVKTSLNQSL FSISKEHLEC R

Sequence

 show evidences
Sequence caution 
The sequence CAA54440 differs from that shown. Reason: erroneous gene model prediction.  
  • CuratedUniProtKB
 

Keywords

Coding sequence diversity 
Alternative splicing  definition   [KW-0025]
Polymorphism  definition   [KW-0621]
Domain 
Homeobox  definition   [KW-0371]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Family and domain databases
Gene3D: 1.10.260.40
Gene3D: 1.10.10.60
InterPro: IPR015586 [ Pit 1 ]
InterPro: IPR013847 [ POU ]
InterPro: IPR009057 [ Homeodomain-like ]
InterPro: IPR000327 [ POU specific ]
InterPro: IPR001356 [ Homeobox dom ]
InterPro: IPR017970 [ Homeobox CS ]
InterPro: IPR010982 [ Lambda DNA-bd dom ]
PANTHER: PTHR11636:SF17 [ PTHR11636:SF17 ]
Pfam: PF00046 [ Homeobox ]
Pfam: PF00157 [ Pou ]
PRINTS: PR00028 [ POUDOMAIN ]
PROSITE: PS51179 [ POU 3 ]
PROSITE: PS50071 [ HOMEOBOX 2 ]
PROSITE: PS00035 [ POU 1 ]
PROSITE: PS00027 [ HOMEOBOX 1 ]
PROSITE: PS00465 [ POU 2 ]
SMART: SM00389 [ HOX ]
SMART: SM00352 [ POU ]
SUPFAM: SSF47413 [ SSF47413 ]
SUPFAM: SSF46689 [ SSF46689 ]
Genome annotation databases
Ensembl: Transcript: ENST00000350375;  Protein: ENSP00000263781;  Gene: ENSG00000064835.
Ensembl: Transcript: ENST00000344265;  Protein: ENSP00000342931;  Gene: ENSG00000064835.
Ensembl: Transcript: ENST00000561167;  Protein: ENSP00000454072;  Gene: ENSG00000064835.
Ensembl: Transcript: ENST00000560656;  Protein: ENSP00000452610;  Gene: ENSG00000064835.
KEGG: hsa:5449
UCSC: uc003dqq.1
Organism-specific databases
MGI: MGI:97588 [ Pou1f1 ]
PTM databases
PhosphoSite: P28069
Phylogenomic databases
eggNOG: NOG241031
HOGENOM: HOG000116302
HOVERGEN: HBG053120
KO: K09363
OMA: TATGLHY
OrthoDB: EOG7DJSMG
Sequence databases
CCDS: CCDS2919.1 [ P28069-1 ]
CCDS: CCDS46873.1 [ P28069-2 ]
EMBL: Genomic DNA:  X77223 , X77224 . Translation:  CAA54441.1 .
EMBL: mRNA:  L18781 . Translation:  AAA60093.1 .
EMBL: Genomic DNA:  X77223 , X77224 . Translation:  CAA54440.2 . Sequence problems.
EMBL: mRNA:  X62429 . Translation:  CAA44295.1 .
EMBL: mRNA:  X72215 . Translation:  CAA51017.1 .
EMBL: Genomic DNA:  D11333 . Translation:  BAA34536.1 .
EMBL: mRNA:  D10216 . Translation:  BAA01068.1 .
EMBL: Genomic DNA:  D12892 . Translation:  BAA02291.1 .
IPI: IPI00216420
IPI: IPI00000794
PIR: S18718
RefSeq: Protein:  NP_000297.1. Nucleotide sequence:  NM_000306.2.
RefSeq: Protein:  NP_001116229.1. Nucleotide sequence:  NM_001122757.1.
UniProtKB: P28069
Protocols and materials databases
DNASU: 5449