PEX2 - Peroxisome biogenesis factor 2 - human protein (Function)
 
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Protein
Gene
References

 
PEX2 »  Peroxisome biogenesis factor 2
 
Protein also known as:  35 kDa peroxisomal membrane protein.
Gene name:  PEX2
Family name: Pex2/pex10/pex12
Entry whose protein(s) existence is based on evidence at protein level
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1 29 1
GENE REF ISO

Function

 show evidences
Overview 
Somewhat implicated in the biogenesis of peroxisomes.  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the peroxisomal protein importer (ppi) family  3.A.20.1.1  
GO molecular function 
Protein bindingdefinition[GO:0005515]  
3
  • IPIIntAct
  • IPIUniProtKB
Zinc ion bindingdefinition[GO:0008270] silver  
  • IEAInterPro 2 GO
GO biological process 
Bile acid biosynthetic processdefinition[GO:0006699] silver  
  • IEAOrtholog Compara
Cholesterol homeostasisdefinition[GO:0042632] silver  
  • IEAOrtholog Compara
Fatty acid beta-oxidationdefinition[GO:0006635]  
2
  • IMPUniProtKB
Negative regulation of epithelial cell proliferationdefinition[GO:0050680]  
1
  • IMPUniProtKB
Negative regulation of fibroblast proliferationdefinition[GO:0048147]  
1
  • IMPUniProtKB
Negative regulation of transcription from RNA polymerase II promoterdefinition[GO:0000122]  
1
  • IMPUniProtKB
Neuron migrationdefinition[GO:0001764] silver  
  • IEAOrtholog Compara
Peroxisome organizationdefinition[GO:0007031]  
2
  • IMPUniProtKB
Protein destabilizationdefinition[GO:0031648]  
1
  • IMPUniProtKB
Protein import into peroxisome matrixdefinition[GO:0016558]  
1
  • IMPUniProtKB
Regulation of cholesterol biosynthetic processdefinition[GO:0045540] silver  
  • IEAOrtholog Compara
Very long-chain fatty acid metabolic processdefinition[GO:0000038]  
1
  • IMPUniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathway:
Peroxisome  hsa04146+5828  
 

Keywords

Biological process 
Peroxisome biogenesis  definition   [KW-0962]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: PXMP3
GenomeRNAi: 5828
PRO: PR:P28328