CHAT - Choline O-acetyltransferase - human protein (Sequence)
 
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Protein
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CHAT »  Choline O-acetyltransferase   [ EC 2.3.1.6 ]  (ChAT)
 
Gene name:  CHAT
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 60 3
GENE REF ISO

Displayed isoform: M     

 
 
Isoform M   748 aaMass: 82536 Da,  pI: 8.9
MGLRTAKKRG LGGGGKWKRE EGGGTRGRRE VRPACFLQSG GRGDPGDVGG PAGNPGCSPH PRAATRPPPL PAHTPAHTPE WCGAASAEAA EPRRAGPHLC IPAPGLTKTP ILEKVPRKMA AKTPSSEESG LPKLPVPPLQ QTLATYLQCM RHLVSEEQFR KSQAIVQQFG APGGLGETLQ QKLLERQEKT ANWVSEYWLN DMYLNNRLAL PVNSSPAVIF ARQHFPGTDD QLRFAASLIS GVLSYKALLD SHSIPTDCAK GQLSGQPLCM KQYYGLFSSY RLPGHTQDTL VAQNSSIMPE PEHVIVACCN QFFVLDVVIN FRRLSEGDLF TQLRKIVKMA SNEDERLPPI GLLTSDGRSE WAEARTVLVK DSTNRDSLDM IERCICLVCL DAPGGVELSD THRALQLLHG GGYSKNGANR WYDKSLQFVV GRDGTCGVVC EHSPFDGIVL VQCTEHLLKH VTQSSRKLIR ADSVSELPAP RRLRWKCSPE IQGHLASSAE KLQRIVKNLD FIVYKFDNYG KTFIKKQKCS PDAFIQVALQ LAFYRLHRRL VPTYESASIR RFQEGRVDNI RSATPEALAF VRAVTDHKAA VPASEKLLLL KDAIRAQTAY TVMAITGMAI DNHLLALREL ARAMCKELPE MFMDETYLMS NRFVLSTSQV PTTTEMFCCY GPVVPNGYGA CYNPQPETIL FCISSFHSCK ETSSSKFAKA VEESLIDMRD LCSLLPPTES KPLATKEKAT RPSQGHQP

Keywords

Coding sequence diversity 
Alternative splicing  definition   [KW-0025]
Polymorphism  definition   [KW-0621]
Technical term 
Direct protein sequencing  definition   [KW-0903]
Reference proteome  definition   [KW-1185]
 

Further external links

Family and domain databases
InterPro: IPR000542 [ Carn acyl trans ]
PANTHER: PTHR22589 [ PTHR22589 ]
Pfam: PF00755 [ Carn acyltransf ]
PROSITE: PS00440 [ ACYLTRANSF C 2 ]
PROSITE: PS00439 [ ACYLTRANSF C 1 ]
Genome annotation databases
Ensembl: Transcript: ENST00000339797;  Protein: ENSP00000343486;  Gene: ENSG00000070748.
Ensembl: Transcript: ENST00000337653;  Protein: ENSP00000337103;  Gene: ENSG00000070748.
Ensembl: Transcript: ENST00000351556;  Protein: ENSP00000345878;  Gene: ENSG00000070748.
Ensembl: Transcript: ENST00000395562;  Protein: ENSP00000378929;  Gene: ENSG00000070748.
Ensembl: Transcript: ENST00000395559;  Protein: ENSP00000378926;  Gene: ENSG00000070748.
Ensembl: Transcript: ENST00000466590;  Protein: ENSP00000473443;  Gene: ENSG00000070748.
Ensembl: Transcript: ENST00000455728;  Protein: ENSP00000390521;  Gene: ENSG00000070748.
KEGG: hsa:1103
UCSC: uc001jhz.2
Organism-specific databases
MGI: MGI:88392 [ Chat ]
Other
EvolutionaryTrace: P28329
PTM databases
PhosphoSite: P28329
Phylogenomic databases
eggNOG: NOG70127
HOGENOM: HOG000233845
HOVERGEN: HBG107717
InParanoid: P28329
KO: K00623
OMA: ATYLQCM
OrthoDB: EOG7WHH90
PhylomeDB: P28329
Sequence databases
CCDS: CCDS7232.1 [ P28329-1 ]
CCDS: CCDS44389.1 [ P28329-2 ]
CCDS: CCDS7233.1 [ P28329-3 ]
EMBL: Genomic DNA:  AF305894 , AF305895 , AF305896 , AF305897 , AF305898 , AF305899 , AF305900 , AF305901 , AF305902 , AF305903 , AF305904 , AF305905 , AF305906 . Translation:  AAK08952.1 .
EMBL: mRNA:  S45018 . Translation:  AAB23557.2 .
EMBL: Genomic DNA:  AC073366 . No translation available.
EMBL: Genomic DNA:  X56879 . Translation:  CAA40201.1 .
EMBL: Genomic DNA:  AF305894 , AF305895 , AF305896 , AF305897 , AF305898 , AF305899 , AF305900 , AF305901 , AF305902 , AF305903 , AF305904 , AF305905 , AF305906 . Translation:  AAK08950.1 .
EMBL: Genomic DNA:  AF305894 , AF305895 , AF305896 , AF305897 , AF305898 , AF305899 , AF305900 , AF305901 , AF305902 , AF305903 , AF305904 , AF305905 , AF305906 . Translation:  AAK08951.1 .
EMBL: mRNA:  AF305909 . Translation:  AAK08955.1 .
EMBL: mRNA:  BC130615 . Translation:  AAI30616.1 .
EMBL: mRNA:  AF305908 . Translation:  AAK08954.1 .
EMBL: mRNA:  S56138 . Translation:  AAA14245.1 .
EMBL: Genomic DNA:  CH471187 . Translation:  EAW93086.1 .
EMBL: Genomic DNA:  X56585 . Translation:  CAA39923.1 .
EMBL: mRNA:  AF305907 . Translation:  AAK08953.1 .
IPI: IPI00220708
IPI: IPI00220707
IPI: IPI00305227
PIR: I52631
RefSeq: Protein:  NP_001136405.1. Nucleotide sequence:  NM_001142933.1.
RefSeq: Protein:  NP_001136401.1. Nucleotide sequence:  NM_001142929.1.
RefSeq: Protein:  NP_066264.3. Nucleotide sequence:  NM_020984.3.
RefSeq: Protein:  NP_066266.3. Nucleotide sequence:  NM_020986.3.
RefSeq: Protein:  NP_066265.3. Nucleotide sequence:  NM_020985.3.
RefSeq: Protein:  NP_001136406.1. Nucleotide sequence:  NM_001142934.1.
RefSeq: Protein:  NP_065574.3. Nucleotide sequence:  NM_020549.4.
UniProtKB: P28329
Protocols and materials databases
DNASU: 1103