CD1C - T-cell surface glycoprotein CD1c - human protein (Function)
 
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CD1C »  T-cell surface glycoprotein CD1c
 
Protein also known as:  CD antigen CD1c.
Gene name:  CD1C
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.  
4
  • CuratedUniProtKB
GO molecular function 
Beta-2-microglobulin bindingdefinition[GO:0030881] silver  
  • IBARefGenome
Endogenous lipid antigen bindingdefinition[GO:0030883]  
1
  • IDAUniProtKB
Exogenous lipid antigen bindingdefinition[GO:0030884]  
1
  • IDAUniProtKB
Glycolipid bindingdefinition[GO:0051861]  
1
  • IDAUniProtKB
Lipopeptide bindingdefinition[GO:0071723]  
1
  • IDAUniProtKB
GO biological process 
Antigen processing and presentation, exogenous lipid antigen via MHC class Ibdefinition[GO:0048007] silver  
  • IBARefGenome
T cell activation involved in immune responsedefinition[GO:0002286]  
1
  • IDAUniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathway:
Hematopoietic cell lineage  hsa04640+911  
 

Keywords

Biological process 
Adaptive immunity  definition   [KW-1064]
Immunity  definition   [KW-0391]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 911
PRO: PR:P29017