MARCKS - Myristoylated alanine-rich C-kinase substrate - human protein (Function)
 
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MARCKS »  Myristoylated alanine-rich C-kinase substrate  (MARCKS)
 
Protein also known as:  Protein kinase C substrate, 80 kDa protein, light chain (PKCSL).
Gene name:  MARCKS
Family name: MARCKS
Entry whose protein(s) existence is based on evidence at protein level
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Function

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Overview 
MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein.  
  • CuratedUniProtKB
GO molecular function 
Actin filament bindingdefinition[GO:0051015]  
1
  • TASPINC
Calmodulin bindingdefinition[GO:0005516]  
  • IEAUniProtKB KW
Protein kinase C bindingdefinition[GO:0005080] silver  
  • IEAOrtholog Compara
Pathways 
According to KEGG, this protein belongs to the following pathway:
Fc gamma R-mediated phagocytosis  hsa04666+4082  
According to Reactome, this protein belongs to the following pathway:
Acetylcholine regulates insulin secretion  REACT_18405  
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: MARCKS
GenomeRNAi: 4082
PRO: PR:P29966