DDT - D-dopachrome decarboxylase - human protein (Function)
 
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Protein
Gene
References

 
DDT »  D-dopachrome decarboxylase   [ EC 4.1.1.84 ]
 
Protein also known as:  Phenylpyruvate tautomerase II.
Gene name:  DDT
Family name: MIF
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Tautomerization of D-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI).  
  • CuratedUniProtKB
GO molecular function 
D-dopachrome decarboxylase activitydefinition[GO:0033981]  
  • IEAEC 2 GO
Dopachrome isomerase activitydefinition[GO:0004167]  
1
  • TASPINC
GO biological process 
Melanin biosynthetic processdefinition[GO:0042438]  
  • IEAUniProtKB KW
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 4.1.1.84: D-dopachrome 5,6-dihydroxyindole + CO(2).  
  • CuratedUniProtKB
 
More information is available from:
Pathways 
According to KEGG, this protein belongs to the following pathway:
Dopaminergic synapse  hsa04728+1652  
 

Keywords

Biological process 
Melanin biosynthesis  definition   [KW-0470]
Molecular function 
Lyase  definition   [KW-0456]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: DDT_(gene)
GenomeRNAi: 1652
PRO: PR:P30046