ALDH1B1 - Aldehyde dehydrogenase X, mitochondrial - human protein (Function)
 
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Protein
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References

 
ALDH1B1 »  Aldehyde dehydrogenase X, mitochondrial   [ EC 1.2.1.3 ]
 
Protein also known as:  Aldehyde dehydrogenase family 1 member B1.
Gene name:  ALDH1B1
Family name: Aldehyde dehydrogenase
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 25 1
GENE REF ISO

Function

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Overview 
ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation.  
  • CuratedUniProtKB
GO molecular function 
Aldehyde dehydrogenase (NAD) activitydefinition[GO:0004029]  
  • IEAEC 2 GO
GO biological process 
Carbohydrate metabolic processdefinition[GO:0005975]  
1
  • NASPINC
Ethanol catabolic processdefinition[GO:0006068]  
  • IEAUniPathway
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 1.2.1.3: An aldehyde + NAD(+) + H(2)O a carboxylate + NADH.  
  • CuratedUniProtKB
Pathways 
This protein is involved in the following pathway
According to KEGG, this protein belongs to the following pathways:
Arginine and proline metabolism  hsa00330+219  
Ascorbate and aldarate metabolism  hsa00053+219  
beta-Alanine metabolism  hsa00410+219  
Fatty acid metabolism  hsa00071+219  
Glycerolipid metabolism  hsa00561+219  
Glycolysis / Gluconeogenesis  hsa00010+219  
Histidine metabolism  hsa00340+219  
Lysine degradation  hsa00310+219  
Metabolic pathways  hsa01100+219  
Pentose and glucuronate interconversions  hsa00040+219  
Propanoate metabolism  hsa00640+219  
Pyruvate metabolism  hsa00620+219  
Tryptophan metabolism  hsa00380+219  
Valine, leucine and isoleucine degradation  hsa00280+219  
 

Keywords

Molecular function 
Oxidoreductase  definition   [KW-0560]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Enzyme and pathway databases
SABIO-RK: P30837
Other
GeneWiki: ALDH1B1
GenomeRNAi: 219
PRO: PR:P30837