NTSR1 - Neurotensin receptor type 1 - human protein (Function)
 
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NTSR1 »  Neurotensin receptor type 1  (NTR1)
 
Protein also known as:  High-affinity levocabastine-insensitive neurotensin receptor.
Gene name:  NTSR1
Entry whose protein(s) existence is based on evidence at protein level
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1 54 1
GENE REF ISO

Function

 show evidences
Overview 
Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.  
2
  • CuratedUniProtKB
GO molecular function 
G-protein coupled neurotensin receptor activitydefinition[GO:0016492]  
1
  • IMPUniProtKB
G-protein coupled receptor activitydefinition[GO:0004930]  
1
  • TASPINC
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
GO biological process 
Adult locomotory behaviordefinition[GO:0008344] silver  
  • IEAOrtholog Compara
G-protein coupled receptor signaling pathwaydefinition[GO:0007186]  
1
  • TASPINC
Neuropeptide signaling pathwaydefinition[GO:0007218]  
1
  • IMPGOC
Synaptic transmissiondefinition[GO:0007268]  
1
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathways:
Calcium signaling pathway  hsa04020+4923  
Neuroactive ligand-receptor interaction  hsa04080+4923  
According to Reactome, this protein belongs to the following pathway:
Signal Transduction  REACT_111102  
 

Keywords

Molecular function 
G-protein coupled receptor  definition   [KW-0297]
Receptor  definition   [KW-0675]
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: Neurotensin_receptor_1
GenomeRNAi: 4923
PRO: PR:P30989
Chemistry
GuidetoPHARMACOLOGY: 309