HOXA9 - Homeobox protein Hox-A9 - human protein (Function)
 
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Protein
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References

 
HOXA9 »  Homeobox protein Hox-A9
 
Protein also known as:  Homeobox protein Hox-1G.
Gene name:  HOXA9
Family name: Abd-B homeobox
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Required for induction of E-selectin and VCAM-1, on the endothelial cells surface at sites of inflammation.  
1
  • CuratedUniProtKB
GO molecular function 
Enzyme bindingdefinition[GO:0019899]  
1
  • IPIUniProtKB
Protein bindingdefinition[GO:0005515]  
2
  • IPIIntAct
Sequence-specific DNA bindingdefinition[GO:0043565] silver  
  • IEAInterPro 2 GO
Sequence-specific DNA binding transcription factor activitydefinition[GO:0003700] silver  
  • IEAInterPro 2 GO
GO biological process 
Endothelial cell activationdefinition[GO:0042118]  
1
  • IMPUniProtKB
Multicellular organismal developmentdefinition[GO:0007275]  
  • IEAUniProtKB KW
Negative regulation of myeloid cell differentiationdefinition[GO:0045638]  
  • ISSOrtholog Curator
Transcription, DNA-templateddefinition[GO:0006351]  
  • IEAUniProtKB KW
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Developmental protein  definition   [KW-0217]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: HOXA9
GenomeRNAi: 3205
PRO: PR:P31269