SLC6A6 - Sodium- and chloride-dependent taurine transporter - human protein (Function)
 
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Protein
Gene
References

 
SLC6A6 »  Sodium- and chloride-dependent taurine transporter
 
Protein also known as:  Solute carrier family 6 member 6.
Gene name:  SLC6A6
Entry whose protein(s) existence is based on evidence at protein level
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1 40 2
GENE REF ISO

Function

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Overview 
Sodium-dependent taurine and beta-alanine transporter. Chloride ions are necessary for optimal uptake.  
2
  • UniProtKB
According to TCDB this is a transporter from family:
the neurotransmitter:sodium symporter (nss) family  2.A.22.3.3  
GO molecular function 
Neurotransmitter:sodium symporter activitydefinition[GO:0005328] silver  
1
  • InterPro 2 GO
Taurine bindingdefinition[GO:0030977] silver  
1
  • Ortholog Compara
Taurine:sodium symporter activitydefinition[GO:0005369] silver  
1
  • Ortholog Compara
GO biological process 
Cellular amino acid metabolic processdefinition[GO:0006520]  
1
  • PINC
Neurotransmitter transportdefinition[GO:0006836]  
1
  • UniProtKB KW
Organic acid transmembrane transportdefinition[GO:1903825]  
3
  • GOC
  • InterPro 2 GO
  • Ortholog Compara
Taurine transportdefinition[GO:0015734] silver  
1
  • Ortholog Compara
Transportdefinition[GO:0006810]  
1
  • PINC
Pathways 
According to Reactome, this protein belongs to the following pathways:
Amino acid transport across the plasma membrane  REACT_13796  
Na+/Cl- dependent neurotransmitter transporters  REACT_20506  
 

Keywords

Biological process 
Neurotransmitter transport  definition   [KW-0532]
Symport  definition   [KW-0769]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: SLC6A6
GenomeRNAi: 6533
PRO: PR:P31641