VIPR1 - Vasoactive intestinal polypeptide receptor 1 - human protein (Function)
 
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VIPR1 »  Vasoactive intestinal polypeptide receptor 1  (VIP-R-1)
 
Protein also known as:  Pituitary adenylate cyclase-activating polypeptide type II receptor (PACAP-R2).
Gene name:  VIPR1
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The affinity is VIP = PACAP-27 > PACAP-38.  
1
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the g-protein-coupled receptor (gpcr) family  9.A.14.4.9  
GO molecular function 
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
Vasoactive intestinal polypeptide receptor activitydefinition[GO:0004999] silver  
  • IEAInterPro 2 GO
GO biological process 
Digestiondefinition[GO:0007586]  
1
  • TASPINC
G-protein coupled receptor signaling pathwaydefinition[GO:0007186]  
1
  • TASPINC
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerdefinition[GO:0007187]  
1
  • TASPINC
Immune responsedefinition[GO:0006955]  
1
  • TASPINC
Muscle contractiondefinition[GO:0006936]  
1
  • TASPINC
Positive regulation of cell proliferationdefinition[GO:0008284]  
1
  • TASPINC
Synaptic transmissiondefinition[GO:0007268]  
1
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathway:
Neuroactive ligand-receptor interaction  hsa04080+7433  
According to Reactome, this protein belongs to the following pathway:
Signal Transduction  REACT_111102  
 

Keywords

Molecular function 
G-protein coupled receptor  definition   [KW-0297]
Receptor  definition   [KW-0675]
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: VIPR1
GenomeRNAi: 7433
PRO: PR:P32241
Chemistry
GuidetoPHARMACOLOGY: 371