ABCD1 - ATP-binding cassette sub-family D member 1 - human protein (Function)
 
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ABCD1 »  ATP-binding cassette sub-family D member 1
 
Protein also known as:  Adrenoleukodystrophy protein (ALDP).
Gene name:  ABCD1
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Probable transporter. The nucleotide-binding fold acts as an ATP-binding subunit with ATPase activity.  
2
  • UniProtKB
According to TCDB this is a transporter from family:
the atp-binding cassette (abc) superfamily  3.A.1.203.3  
GO molecular function 
ATP bindingdefinition[GO:0005524]  
1
  • UniProtKB
ATPase activitydefinition[GO:0016887]  
1
  • UniProtKB
ATPase activity, coupled to transmembrane movement of substancesdefinition[GO:0042626]  
1
  • UniProtKB
Enzyme bindingdefinition[GO:0019899]  
1
  • UniProtKB
Identical protein bindingdefinition[GO:0042802]  
1
  • IntAct
Peroxisomal fatty-acyl-CoA transporter activitydefinition[GO:0005325]  
1
  • UniProtKB
Protein bindingdefinition[GO:0005515]  
5
  • IntAct
  • UniProtKB
Protein homodimerization activitydefinition[GO:0042803]  
3
  • UniProtKB
Transporter activitydefinition[GO:0005215]  
1
  • UniProtKB
GO biological process 
Fatty acid beta-oxidationdefinition[GO:0006635]  
4
  • UniProtKB
Long-chain fatty acid catabolic processdefinition[GO:0042758]  
1
  • UniProtKB
Peroxisomal long-chain fatty acid importdefinition[GO:0015910]  
1
  • UniProtKB
Peroxisomal membrane transportdefinition[GO:0015919]  
1
  • UniProtKB
Peroxisome organizationdefinition[GO:0007031]  
2
  • UniProtKB
Very long-chain fatty acid catabolic processdefinition[GO:0042760]  
3
  • UniProtKB
Enzymatic activity 
 
More information is available from:
Pathways 
According to KEGG, this protein belongs to the following pathways:
ABC transporters  hsa02010+215  
Peroxisome  hsa04146+215  
According to Reactome, this protein belongs to the following pathways:
ABCA transporters in lipid homeostasis  REACT_111158  
alpha-linolenic acid (ALA) metabolism  REACT_121147  
Beta-oxidation of very long chain fatty acids  REACT_17062  
Linoleic acid (LA) metabolism  REACT_121100  
 

Keywords

Biological process 
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ABCD1
GenomeRNAi: 215
PRO: PR:P33897